676144-17-5

Basic information

• Product Name: C₆₅H₉₃F₅O₁₃S
• Synonyms: C₆₅H₉₃F₅O₁₃S
• CAS NO: 676144-17-5
• Molecular Weight: 1209.5
• Mol File: 676144-17-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₆₅H₉₃F₅O₁₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₅H₉₃F₅O₁₃S(676144-17-5)
• EPA Substance Registry System: C₆₅H₉₃F₅O₁₃S(676144-17-5)

Safety Data

• Hazardous Substances Data: 676144-17-5(Hazardous Substances Data)

Upstream product

• 103366-74-1 2,3,4,6-Tetra-O-pivaloyl-α-D-glucopyranosyl trichloroacetimidate 
• 261506-25-6 fulvestrant 3-benzoate 
• 114179-84-9 1,2,3,4,6-penta-O-pivaloyl-D-glucopyranoside 
• 148968-87-0 2,3,4,6-Tetra-O-pivaloyl-α/β-D-glucopyranose 

Relevant articles and documents

Sugar conjugates of fulvestrant (ICI 182,780): Efficient general procedures for glycosylation of the fulvestrant core

We have prepared glucose and cellobiose conjugates at the phenolic 3- and hydroxylic 17-positions of the pure anti-estrogenic compound fulvestrant (ICI 182,780), which has recently been approved in the USA for the treatment of advanced postmenopausal breast cancer. Glycosylation at the 17-position was achieved most effectively using pivaloyl protection of the sugar imidates employed, which we found suppressed the competing transacylation reaction and led to improved yields of the product glycosides.