67617-35-0

Usage

InChI:InChI=1/C10H21NO2.ClH/c1-7(2)6-8(11)9(12)13-10(3,4)5;/h7-8H,6,11H2,1-5H3;1H/t8-;/m1./s1

Upstream product

• 339304-38-0 tert-butyl (R)-2-amino-4-methylpent-4-enoate 
• 611182-64-0 (2R,3S)-3-[4-(triisopropylsilanyloxy)phenyl]oxirane-2-carboperoxoic acid tert-butyl ester 
• 75716-87-9 tert-butyl 4-methyl-2-oxopentanoate 

Downstream Products

• 1215220-09-9 C₂₆H₂₉N₃O₃ 
• 529496-47-7 2-[7-(3,5-dimethoxy-benzylamino)-1,1-dioxo-1,3,4,5-tetrahydro-1λ⁶-benzo[f][1,2,5]thiadiazepin-2-yl]-4-methyl-pentanoic acid benzyloxy-amide 
• 529496-45-5 tert-butyl (2R)-2-[7-[(3,5-dimethoxybenzyl)oxy]-1,1-dioxido-4,5-dihydro-1,2,5-benzothiadiazepin-2(3H)-yl]-4-methylpentanoate 
• 529496-46-6 2-[7-(3,5-dimethoxy-benzylamino)-1,1-dioxo-1,3,4,5-tetrahydro-1λ⁶-benzo[f][1,2,5]thiadiazepin-2-yl]-4-methyl-pentanoic acid 
• 238405-88-4 (R)-2-(7-{[1-(3,5-Dimethoxy-phenyl)-meth-(E)-ylidene]-amino}-1,1-dioxo-1,3,4,5-tetrahydro-1λ⁶-benzo[f][1,2,5]thiadiazepin-2-yl)-4-methyl-pentanoic acid tert-butyl ester 
• 238405-78-2 2-[(2-bromo-ethyl)-(2,4-dinitro-benzenesulfonyl)-amino]-4-methyl-pentanoic acid tert-butyl ester 
• 238405-79-3 2-[(2-bromo-ethyl)-(2,4-diamino-benzenesulfonyl)-amino]-4-methyl-pentanoic acid tert-butyl ester 
• 238405-77-1 2-(2,4-dinitro-benzenesulfonylamino)-4-methyl-pentanoic acid tert-butyl ester 

Relevant academic research and scientific papers

Asymmetric Synthesis of α-Amino Acids by Organocatalytic Biomimetic Transamination

A biomimetic enantioselective transamination of α-keto ester derivatives can be realized under mild conditions by using chiral quaternary ammonium arenecarboxylates in the absence of base additives. The corresponding α-amino acids can be used as versatile intermediates for further synthetic transformations that furnish chiral pyrrolidine and octahydroindolizine derivatives.

An efficient asymmetric biomimetic transamination of α-keto esters to chiral α-amino esters

An efficient asymmetric biomimetic transamination of α-keto esters with quinine derivatives as chiral bases was described. A wide variety of α-amino esters containing various functional groups can be synthesized in high yield and enantioselectivity.

Enantioselective syntheses of aeruginosin 298-A and its analogues using a catalytic asymmetric phase-transfer reaction and epoxidation

We developed a versatile synthetic process for aeruginosin 298-A as well as several attractive analogues, in which all stereocenters were controlled by a catalytic asymmetric phase-transfer reaction and epoxidation. Furthermore, drastic counteranion effects in phase-transfer catalysis were observed for the first time, making it possible to three-dimensionally fine-tune the catalyst (ketal part, aromatic part, and counteranion). Copyright