67618-39-7Relevant academic research and scientific papers
BROMINATION OF 2-THIAZOLYLHYDRAZONES
Usol'tseva, S. V.,Andronnikova, G. P.,Shevyrin, V. A.
, p. 226 - 230 (2007/10/02)
Bromination of the 4-carbethoxy- and 4-carboxy-2-thiazolylhydrazones of aldehydes and ketones occurs principally at the 5 position of the thiazole ring.In the case of aldehyde hydrazones an excess of bromine leads to substitution of the methine hydrogen atom and to intramolecular cyclization of the intermediate halohydrazone to 1,2,4-triazolothiazole.
