676264-75-8

Upstream product

• 342612-67-3 (S)-3-Cyclohexyl-2-((2S,3S)-3-methyl-2-{(S)-4-methyl-2-[(pyrazine-2-carbonyl)-amino]-pentanoylamino}-pentanoylamino)-propionic acid 
• 676262-11-6 (S)-2-[(2S,3S)-2-((S)-2-tert-Butoxycarbonylamino-4-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-cyclohexyl-propionic acid 
• 558475-58-4 {1-[2-Cyano-2-(triphenyl-λ⁵-phosphanylidene)-acetyl]-cyclopropyl}-carbamic acid benzyl ester 
• 676262-42-3 (S)-2-[(2S,3S)-2-((S)-2-Amino-4-methyl-pentanoylamino)-3-methyl-pentanoylamino]-3-cyclohexyl-propionic acid 
• 342612-66-2 (S)-2-((2S,3S)-2-tert-Butoxycarbonylamino-3-methyl-pentanoylamino)-3-cyclohexyl-propionic acid 
• 558475-60-8 [2-(1-benzyloxycarbonylamino-cyclopropyl)-2-oxo-acetylamino]-acetic acid tert-butyl ester 
• 676261-87-3 (S)-2-((2S,3S)-2-Amino-3-methyl-pentanoylamino)-3-cyclohexyl-propionic acid 
• 3392-08-3 N-(tert-butoxy)carbonyl-L-isoleucine N-hydroxysuccinimide ester 
• 27532-96-3 glycine tert-butyl ester hydrochloride 
• 27527-05-5 L-cyclohexylalanine 
• 3392-09-4 Boc-Leu-ONSu 
• 558475-62-0 (2-{1-[(S)-3-Cyclohexyl-2-((2S,3S)-3-methyl-2-{(S)-4-methyl-2-[(pyrazine-2-carbonyl)-amino]-pentanoylamino}-pentanoylamino)-propionylamino]-cyclopropyl}-2-hydroxy-acetylamino)-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

Glycine α-ketoamides as HCV NS3 protease inhibitors

Using a tetrapeptide-based α-ketoamide template, various amines and amino acids were incorporated to explore the prime side of the HCV NS3 protease catalytic site. Glycine carboxylic acid was found to be the most effective prime group. Further optimizatio