676264-80-5Relevant academic research and scientific papers
Conformationally restricted homotryptamines. part 7: 3- cis -(3-aminocyclopentyl)indoles as potent selective serotonin reuptake inhibitors
King, H. Dalton,Meng, Zhaoxing,Deskus, Jeffrey A.,Sloan, Charles P.,Gao, Qi,Beno, Brett R.,Kozlowski, Edward S.,Lapaglia, Melissa A.,Mattson, Gail K.,Molski, Thaddeus F.,Taber, Matthew T.,Lodge, Nicholas J.,Mattson, Ronald J.,MacOr, John E.
experimental part, p. 7564 - 7572 (2011/02/21)
A series of conformationally restricted homotryptamines has been synthesized and shown to be potent inhibitors of hSERT. Conformational restriction of the homotryptamine side chain was attained by the insertion of a cyclopentyl ring, with the indole ring
