676266-99-2

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(4-CHLORO-PHENYL)-HEXANE-1,4-DIONE is used as an intermediate in the synthesis of pharmaceuticals due to its ability to participate in various chemical reactions. Its versatility allows for the creation of a wide range of organic molecules with potential medicinal applications.
Used in Organic Chemistry:
As a building block in organic chemistry, 1-(4-CHLORO-PHENYL)-HEXANE-1,4-DIONE is used for its capacity to undergo reduction, acetylation, and alkylation reactions. This enables the synthesis of diverse chemical compounds for research and industrial purposes.
Used in Dye and Pigment Production:
The unique properties of the chlorophenyl group in 1-(4-CHLORO-PHENYL)-HEXANE-1,4-DIONE make it useful in the production of dyes and pigments. Its application in this industry contributes to the development of new colorants and materials with specific characteristics.

InChI:InChI=1/C12H13ClO2/c1-2-11(14)7-8-12(15)9-3-5-10(13)6-4-9/h3-6H,2,7-8H2,1H3

Upstream product

• 75-11-6 diiodomethane 
• 26732-06-9 1-(4-chlorophenyl)pentane-1,3-dione 
• 1629-58-9 4-penten-3-one 
• 104-88-1 4-chlorobenzaldehyde 
• 99-91-2 para-chloroacetophenone 
• 816-40-0 1-Bromo-2-butanone 

Relevant academic research and scientific papers

1,5-Diaryl-2-ethyl pyrrole derivatives as antimycobacterial agents: Design, synthesis, and microbiological evaluation

During the search of novel antitubercular drugs related to BM 212, new diarylpyrroles were designed and synthesized on the basis of a structure-activity relationship analysis of many pyrroles previously described by us. Among them, 1-(4-fluorophenyl)-2-et

Zinc-mediated chain extension reaction of 1,3-diketones to 1,4-diketones and diastereoselective synthesis of trans-1,2-disubstituted cyclopropanols

A variety of 1,3-diketones can be efficiently converted into the corresponding 1,4-diketones and trans-1,2-disubstituted cyclopropanols by using organozinc species in one-pot reactions. It was found that 2.3 equiv of CF 3CO2ZnCH2I was effective to give the corresponding chain-extended products in 44-85% yields, while a mixture of organozinc species formed from 4.0 equiv of Et2Zn, 2.0 equiv of CF3CO2H, and 4.0 equiv of CH2I2 resulted in the formation of trans-1,2-disubstituted cyclopropanols with quite good yields and diastereoselectivity.

PYRROLE DERIVATIVES AS ANTIMYCOBACTERIAL COMPOUNDS

Novel pyrrole derivatives of formula (I), and their pharmaceutically acceptable acid addition salts having superior antimycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis as well as having lesser