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676348-49-5

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676348-49-5 Usage

General Description

(E)-3-(4-bromo-2-fluorophenyl)acryloyl chloride is a chemical compound with the molecular formula C9H5BrClF. It is an acryloyl chloride derivative, which means it contains a reactive acyl chloride group attached to an acryloyl group. (E)-3-(4-BROMO-2-FLUOROPHENYL)ACRYLOYL CHLORIDE is used as a building block in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. The (E)-configuration indicates that the bromine and fluorine substituents are on opposite sides of the double bond in the acryloyl group. It is a highly reactive compound and should be handled with care, as it can react vigorously with water and alcohols, releasing toxic hydrogen chloride gas.

Check Digit Verification of cas no

The CAS Registry Mumber 676348-49-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,6,3,4 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 676348-49:
(8*6)+(7*7)+(6*6)+(5*3)+(4*4)+(3*8)+(2*4)+(1*9)=205
205 % 10 = 5
So 676348-49-5 is a valid CAS Registry Number.

676348-49-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-3-(4-Bromo-2-fluorophenyl)acryloylchloride

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:676348-49-5 SDS

676348-49-5Relevant articles and documents

Design, Synthesis, Structure-Activity Relationship, Molecular Docking, and Herbicidal Evaluation of 2-Cinnamoyl-3-Hydroxycyclohex-2-en-1-one Derivatives as Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors

Song, Hao-Min,Zhao, Li-Xia,Zhang, Shuai-Qi,Ye, Tong,Fu, Ying,Ye, Fei

, p. 12621 - 12633 (2021/11/13)

Cinnamic acid, isolated from cinnamon bark, is a natural product with excellent bioactivity, and it effectively binds with cyclohexanedione to form novel 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibitors. According to the active sub-structure combinat

PHARMACEUTICALLY ACTIVE BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES

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Page 47, (2010/02/07)

Compounds of formula (I): wherein R1, R2 and R3 are independently, hydrogen, halogen, CF3, OR6, NR7R8, NR8COR10, NR8SO2R10 or C1-6 alkyl optionally substituted by hydroxy, C1-6 alkoxy or NR7R8; R4 is NR8CONR8R9, NR8COR9, NR8SO2R9, or W-CONR8R9, where W is a bond, C1-6 alkylene, C2-6 alkenylene or C2-6 alkynylene; and R5 is Formula (A) methods for their synthesis, pharmaceutical compositions comprising them and their use in medicine, in particular for the treatment of cancer.

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