676371-75-8Relevant articles and documents
3-Aminobicyclo[1.1.1]pentane-1-carboxylic Acid Derivatives: Synthesis and Incorporation into Peptides
Paetzel, Michael,Sanktjohanser, Maximilian,Doss, Alexander,Henklein, Peter,Szeimies, Guenter
, p. 493 - 498 (2007/10/03)
We have developed an efficient synthesis of derivatives of 3-aminobicyclo[1.1.1]pentane-1-carboxylic acid (7, 8, 9, and 10) starting from [1.1.1]propellane (3). These rigid analogues of γ-aminobutyric acid have been incorporated into linear and cyclic peptides using solution chemistry and solid-phase techniques. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.