676449-14-2

Basic information

• Product Name: 3-Pyrrolidinol, 2-[(4-methoxyphenyl)methyl]-4-methyl-1-(phenylmethyl)-, acetate (ester), (2R,3R,4S)-
• CAS NO: 676449-14-2
• Molecular Formula: C22H27NO3
• Molecular Weight: 353.461
• Mol File: 676449-14-2.mol

Chemical Properties

• CAS DataBase Reference: 3-Pyrrolidinol, 2-[(4-methoxyphenyl)methyl]-4-methyl-1-(phenylmethyl)-, acetate (ester), (2R,3R,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyrrolidinol, 2-[(4-methoxyphenyl)methyl]-4-methyl-1-(phenylmethyl)-, acetate (ester), (2R,3R,4S)-(676449-14-2)
• EPA Substance Registry System: 3-Pyrrolidinol, 2-[(4-methoxyphenyl)methyl]-4-methyl-1-(phenylmethyl)-, acetate (ester), (2R,3R,4S)-(676449-14-2)

Safety Data

• Hazardous Substances Data: 676449-14-2(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 676449-13-1 (2R,3R,4S)-1-benzyl-3-hydroxy-2-(4-methoxybenzyl)-4-methylpyrrolidine 
• 676449-10-8 (2'R,3'R,4R,4'R)-3-[4'-N,N-dibenzylamino-3'-hydroxy-5'-(4-methoxyphenyl)-2'-methyl-1'-oxopentyl]-4-phenylmethyloxazolidin-2-one 
• 676449-11-9 (2S,3R,4R)-4-N,N-dibenzylamino-3-hydroxy-5-(4-methoxyphenyl)-2-methylpentan-1-ol 

Relevant articles and documents

Synthetic anisomycin analogues activating the JNK/SAPK1 and p38/SAPK2 pathways

The synthesis of C(4)H and C(4)Me analogues of the JNK/p38 pathway activator anisomycin, based upon an aldol or Claisen construction of the C(3)-C(4) bond, has been demonstrated. The relative activation of the JNK/SAPK1 and p38/SAPK2 pathways in RAW macrophages by these analogues, and their synthetic precursors, has been assessed using immunoblot assays against phosphorylated c-Jun and MAPKAP-K2. These studies demonstrate that some of the synthetic C(4) analogues are also potent activators of these stress kinase pathways.