676487-05-1

Upstream product

• 676486-88-7 [tert-butoxycarbonylimino-(2-oxa-3-aza-bicyclo[2.2.2]oct-5-en-3-yl)methyl]-carbamic acid tert-butyl ester 
• 676486-87-6 N,N'-di-tert-butoxycarbonyl-N''-hydroxylguanidine 
• 322474-21-5 N,N'-bis-Boc-S-methyl-isothiourea 
• 24424-99-5 di-tert-butyl dicarbonate 
• 676487-04-0 [tert-butoxycarbonylimino-(2-oxa-3-aza-bicyclo[2.2.2]oct-3-yl)methyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Hetero Diels-Alder reactions of nitrosoamidines: An efficient method for the synthesis of functionalized guanidines

Hetero Diels-Alder reactions of transient nitrosoamidines are reported. Transient nitrosoamidines are formed by oxidation of protected N-hydroxylguanidines and are trapped in situ by 1,3-dienes to give [4 + 2] cycloadducts in good yields and regioselectivity. The resultant cycloadducts are versatile intermediates for the formation of functionalized guanidines.