676528-97-5Relevant academic research and scientific papers
Synthetic method of nitrogen-containing heterocyclic ring compound and intermediate of nitrogen-containing heterocyclic ring compound
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Paragraph 0160-0165, (2022/03/27)
The invention relates to a nitrogen-containing heterocyclic ring compound and an intermediate synthesis method thereof. The synthesis method of the intermediate comprises the following step: carrying out photochemical reaction on a compound 1 and a compound 2 to prepare the intermediate. The synthesis method is mild in reaction condition, easy in reaction control and short in synthesis route, and has an industrial production prospect.
PYRAZOLOPYRIMIDIN-2-YL DERIVATIVES AS JAK INHIBITORS
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Page/Page column 79; 80, (2015/06/25)
New pyrazolopyridmiin-2-yl derivatives are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).
COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY
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Page/Page column 51-52, (2009/11/29)
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of GPR119; such as, but not limited to, diabetes, obesity and associated metabolic disorders. Formula (I) is a compound, in which A can have up to 2 ring -CH2- group substituted with -C(O)- and can be partially unsaturated with up to 2 double bonds; Wi and W2 are independently selected from CR10 and N; wherein R10 is selected from hydrogen and C1_6alkyl; Yi is selected from NRn, O and S; wherein Rn is selected from hydrogen and C1_ 6alkyl; Y2 and Y3 are independently selected from CH and N; Y4 is selected from CH2, OCH2 and NR15; wherein R15 is selected from hydrogen and C1_6alkyl; or the pharmaceutically acceptable salts thereof.
