676599-93-2Relevant academic research and scientific papers
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a New Class of Synthetic Histone Deacetylase Inhibitors. 3. Discovery of Novel Lead Compounds through Structure-Based Drug Design and Docking Studies
Ragno, Rino,Mai, Antonello,Massa, Silvio,Cerbara, Ilaria,Valente, Sergio,Bottoni, Patrizia,Scatena, Roberto,Jesacher, Florian,Loidl, Peter,Brosch, Gerald
, p. 1351 - 1359 (2004)
Aroyl-pyrrole-hydroxy-amides (APHAs) are a new class of synthetic HDAC inhibitors recently described by us. Through three different docking procedures we designed, synthesized, and tested two new isomers of APHA lead compound 3-(4-benzoyl-1-methyl-1H-pyrr
