676607-31-1

Usage

Uses

Used in Pharmaceutical Industry:
TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE is used as a building block for the synthesis of various pharmaceuticals and bioactive molecules due to its unique structure and properties. Its spirocyclic nature and functional groups make it a promising candidate for drug development and discovery.
Used in Organic Synthesis:
In the field of organic synthesis, TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE serves as a valuable intermediate for the preparation of complex organic compounds. Its stability and solubility under various reaction conditions facilitate its use in the synthesis of a wide range of molecules.
Used in Medicinal Chemistry:
TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE is utilized in medicinal chemistry for the design and development of novel therapeutic agents. Its unique structure and functional groups allow for the exploration of new chemical space and the identification of potential drug candidates with improved pharmacological properties.

Upstream product

• 676607-30-0 1'-benzyloxycarbonyl-1-tert-butyloxycarbonylspiro[indoline-3,4'-piperidine] 
• 167484-18-6 benzyl spiro[indoline-3,4’-piperidine]-1‘-carboxylate 
• 138163-08-3 N-(benzyloxycarbonyl)piperidine-4-carboxaldehyde 
• 823-85-8 4-fluorophenyhydrazine hydrochloride 
• 867009-74-3 C₂₄H₃₀N₂O₂ 

Relevant academic research and scientific papers

COMPOUNDS AND THERAPEUTIC USES THEREOF

The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and complications associated w

Novel Spiropiperidine Compounds

A compound of the formula: or a pharmaceutically acceptable salt thereof as well as a pharmaceutical composition, and a method for treating diabetes.

SUBSTITUTED DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES AND THEIR USE AS NEUROKININ ANTAGONISTS

This invention concerns substituted diaza-spiro-[4.5]-decane derivatives having neurokinin antagonistic activity, in particular NK1 antagonistic activity, a combined NK1/NK2 antagonist ic activity, a combined NK1/NK3 antagonist ic activity and a combined NK1/NK2/NK3 antagonistic activity, their preparation, compositions comprising them and their use as a medicine, in particular for the treatment and/or prophylaxis of schizophrenia, emesis, anxiety and depression, irritable bowel syndrome (IBS), circadian rhythm disturbances, pre-eclampsia, nociception, pain, in particular visceral and neuropathic pain, pancreatitis, neurogenic inflammation, asthma, chronic obstructive pulmonary disease (COPD) and micturition disorders such as urinary incontinence. The compounds according to the invention can be represented by general Formula (I) and comprises also the pharmaceutically acceptable acid or base addition salts thereof, the stereochemically isomeric forms thereof, the N-oxide form thereof and prodrugs thereof, wherein all substituents are defined as in Claim 1.