676607-31-1

Basic information

• Product Name: TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE
• Synonyms: TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE;diazaspiro[4.5]decane-2-carboxylate-1(2H)-carboxylate;tert-butyl 1,2-dihydrospiro[indole-3,4'-piperidine]-1-carboxylate;Spiro[3H-indole-3,4-piperidine]-1(2H)-carboxylic acid, 1,1-diMethethylethyl ester;Spiro[indole-3,4'-piperindine]-1(2H)-carboxylate tert-butyl ester;Spiro[3H-indole-3,4'-piperidine]-1(2H)-carboxylic acid 1,1-dimethyl ethyl ester;tert-Butyl 2H-spiro[indole-3,4'-piperidine]-1-carboxylate
• CAS NO: 676607-31-1
• Molecular Formula: C17H24N2O2
• Molecular Weight: 288.39
• Mol File: 676607-31-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE(676607-31-1)
• EPA Substance Registry System: TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE(676607-31-1)

Safety Data

• Hazardous Substances Data: 676607-31-1(Hazardous Substances Data)

Usage

General Description

TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE is a chemical compound that belongs to the class of spiro compounds. It is commonly used in organic synthesis and medicinal chemistry as a building block for various pharmaceuticals and bioactive molecules. TERT-BUTYL SPIRO[INDOLE-3,4'-PIPERIDINE]-1(2H)-CARBOXYLATE has a spirocyclic structure, with an indole and a piperidine ring connected through a spiro carbon atom. The tert-butyl group and carboxylate functional group attached to the spiro carbon provide stability and solubility to the compound, making it suitable for use in various reaction conditions. Additionally, its unique structure and properties make it a potential candidate for drug development and discovery.

Upstream product

• 676607-30-0 1'-benzyloxycarbonyl-1-tert-butyloxycarbonylspiro[indoline-3,4'-piperidine] 
• 167484-18-6 benzyl spiro[indoline-3,4’-piperidine]-1‘-carboxylate 
• 138163-08-3 N-(benzyloxycarbonyl)piperidine-4-carboxaldehyde 
• 823-85-8 4-fluorophenyhydrazine hydrochloride 
• 867009-74-3 C₂₄H₃₀N₂O₂ 

Relevant articles and documents

COMPOUNDS AND THERAPEUTIC USES THEREOF

The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and complications associated w

SUBSTITUTED DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES AND THEIR USE AS NEUROKININ ANTAGONISTS

This invention concerns substituted diaza-spiro-[4.5]-decane derivatives having neurokinin antagonistic activity, in particular NK1 antagonistic activity, a combined NK1/NK2 antagonist ic activity, a combined NK1/NK3 antagonist ic activity and a combined NK1/NK2/NK3 antagonistic activity, their preparation, compositions comprising them and their use as a medicine, in particular for the treatment and/or prophylaxis of schizophrenia, emesis, anxiety and depression, irritable bowel syndrome (IBS), circadian rhythm disturbances, pre-eclampsia, nociception, pain, in particular visceral and neuropathic pain, pancreatitis, neurogenic inflammation, asthma, chronic obstructive pulmonary disease (COPD) and micturition disorders such as urinary incontinence. The compounds according to the invention can be represented by general Formula (I) and comprises also the pharmaceutically acceptable acid or base addition salts thereof, the stereochemically isomeric forms thereof, the N-oxide form thereof and prodrugs thereof, wherein all substituents are defined as in Claim 1.