676626-83-8

Basic information

• Product Name: 3-methyl-2-oxo-3-m-tolyl-butyric acid
• CAS NO: 676626-83-8
• Molecular Weight: 206.241
• Mol File: 676626-83-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-2-oxo-3-m-tolyl-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-2-oxo-3-m-tolyl-butyric acid(676626-83-8)
• EPA Substance Registry System: 3-methyl-2-oxo-3-m-tolyl-butyric acid(676626-83-8)

Safety Data

• Hazardous Substances Data: 676626-83-8(Hazardous Substances Data)

Upstream product

• 61676-25-3 2-oxo-3-m-tolyl-propionic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 676631-42-8 (E)-(S)-4-{[(S)-3,3-Dimethyl-2-((R)-3-methyl-2-methylamino-3-m-tolyl-butyrylamino)-butyryl]-methyl-amino}-2,5-dimethyl-hex-2-enoic acid ethyl ester 
• 676631-78-0 (E)-(S)-4-{[(S)-3,3-Dimethyl-2-((S)-3-methyl-2-methylamino-3-m-tolyl-butyrylamino)-butyryl]-methyl-amino}-2,5-dimethyl-hex-2-enoic acid ethyl ester 
• 676626-85-0 3-methyl-2-methylamino-3-m-tolyl-butyric acid 
• 676631-81-5 N,β,β,3-tetramethyl-L-phenylalanyl-N1-[(1S,2E)-3-carboxy-1-isopropyl-2-butenyl]-N1,3-dimethyl-L-valinamide 

Relevant articles and documents

Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: Modification of the a segment

Analogs of HTI-286 (1), containing various aromatic rings in the A segment, were synthesized as potential inhibitors of tubulin polymerization, and the structure-activity relationships related to stereo- and regio-chemical effects of substituents on the a