676629-19-9Relevant academic research and scientific papers
Pyridine-3-carboxamides as novel CB2 agonists for analgesia
Mitchell, William L.,Giblin, Gerard M.P.,Naylor, Alan,Eatherton, Andrew J.,Slingsby, Brian P.,Rawlings, Anthony D.,Jandu, Karamjit S.,Haslam, Carl P.,Brown, Andrew J.,Goldsmith, Paul,Clayton, Nick M.,Wilson, Alex W.,Chessell, Iain P.,Green, Richard H.,Whittington, Andrew R.,Wall, Ian D.
scheme or table, p. 259 - 263 (2009/05/26)
We describe herein the medicinal chemistry approach which led to the discovery of a novel pyridine-3-carboxamide series of CB2 receptor agonists. The SAR of this new template was evaluated and culminated in the identification of analogue 14a wh
COMBINATION OF CB2 MODULATORS AND PDE4 INHIBITORS FOR USE IN MEDICINE
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Page/Page column 146, (2010/02/13)
Combination of one or more CB2 modulators such as a compound of formula (I), (II) and (III); and one more PDE4 inhibitors are useful of treating conditions which are mediated by the activity of CB2 receptors or conditions which are mediated by PDE4, such
PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS
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, (2010/02/06)
The present invention relates to novel pyridine derivatives of formula (I) pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increas
PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS
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Page 59, (2010/02/06)
The present invention relates to novel pyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease
