676630-75-4Relevant articles and documents
Pyridine-3-carboxamides as novel CB2 agonists for analgesia
Mitchell, William L.,Giblin, Gerard M.P.,Naylor, Alan,Eatherton, Andrew J.,Slingsby, Brian P.,Rawlings, Anthony D.,Jandu, Karamjit S.,Haslam, Carl P.,Brown, Andrew J.,Goldsmith, Paul,Clayton, Nick M.,Wilson, Alex W.,Chessell, Iain P.,Green, Richard H.,Whittington, Andrew R.,Wall, Ian D.
scheme or table, p. 259 - 263 (2009/05/26)
We describe herein the medicinal chemistry approach which led to the discovery of a novel pyridine-3-carboxamide series of CB2 receptor agonists. The SAR of this new template was evaluated and culminated in the identification of analogue 14a wh