67681-84-9 Usage
Uses
Used in Pharmaceutical Industry:
6-Chloro-1-Ethyl-4-Oxo-7-(Piperazin-1-yl)-1,4-Dihydroquinoline-3-Carboxylic acid is used as an antibiotic for treating various bacterial infections, including respiratory, urinary, skin, and prostate infections. Its ability to inhibit the DNA gyrase enzyme makes it effective against a broad spectrum of bacteria.
Used in Hospital Settings:
In hospitals and healthcare facilities, 6-Chloro-1-Ethyl-4-Oxo-7-(Piperazin-1-yl)-1,4-Dihydroquinoline-3-Carboxylic acid is used as a therapeutic agent to combat bacterial infections in patients, particularly those with compromised immune systems or who are at a higher risk of developing infections.
Used in Outpatient Treatment:
6-Chloro-1-Ethyl-4-Oxo-7-(Piperazin-1-yl)-1,4-Dihydroquinoline-3-Carboxylic acid is used as an oral antibiotic for outpatient treatment of mild to moderate bacterial infections, providing a convenient and effective option for patients to manage their infections without hospitalization.
However, it is important to note that levofloxacin has been associated with some serious side effects, such as tendon rupture and nerve damage. Therefore, it should be used with caution, especially in certain high-risk patient populations, and under the guidance of a healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 67681-84-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,6,8 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 67681-84:
(7*6)+(6*7)+(5*6)+(4*8)+(3*1)+(2*8)+(1*4)=169
169 % 10 = 9
So 67681-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H18ClN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
67681-84-9Relevant academic research and scientific papers
Structure-Activity Relationships of Antibacterial 6,7- and 7,8-Disubstituted 1-Alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic Acids
Koga, Hiroshi,Itoh, Akira,Murayama, Satoshi,Suzue, Seigo,Irikura, Tsutomu
, p. 1358 - 1363 (2007/10/02)
Previous quantitative and qualitative structure-activity studies in antibacterial monosubstituted 1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids prompted us to synthesize the 6,7,8-polysubstituted compounds.In this paper, the preparation and antibacterial activity of the 6,7- and 7,8-disubstituted compounds and their derivatives are described.Among these compounds, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid (34) possessed many significant activities and was more active than oxolinic acid (84) against Gram-positive andGram-negative bacteria.Structure activity relationships are discussed.
