67686-06-0

Basic information

• Product Name: Nsc240911
• Synonyms: Nsc240911;(1-Methyl-piperidin-4-yl)-acetic acidhydrochloride;1-Methyl-4-piperidineacetic acid HCl;2-(1-methylpiperidin-4-yl)acetic acid hydrochloride;(1-Methyl-piperidin-4-yl)-acetic acid x HCl, 98%
• CAS NO: 67686-06-0
• Molecular Formula: C8H15NO2.ClH
• Molecular Weight: 193.672
• Mol File: 67686-06-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Nsc240911(CAS DataBase Reference)
• NIST Chemistry Reference: Nsc240911(67686-06-0)
• EPA Substance Registry System: Nsc240911(67686-06-0)

Safety Data

• Hazardous Substances Data: 67686-06-0(Hazardous Substances Data)

Usage

General Description

Nsc240911, also known as WZ4003, is a selective and potent inhibitor of atypical protein kinase C (aPKC) isoforms. It has been found to selectively inhibit aPKCι and aPKCζ in both in vitro and in vivo studies. Nsc240911 has been shown to induce apoptosis in cancer cells with elevated aPKC activity, and has demonstrated efficacy in inhibiting the growth of various cancer cell lines, including breast, prostate, and colon cancer. Additionally, Nsc240911 has been investigated for its potential in combination therapy with other cancer treatments, and has shown promising results in preclinical studies. Overall, Nsc240911 is a promising chemical compound with potential therapeutic applications in cancer treatment.