67694-96-6

Upstream product

• 31352-60-0 (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl phenylphosphinate 
• 31352-60-0 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl phenylphosphinate 
• 67694-97-7 menthylchloro(phenyl)phosphonate 

Downstream Products

• 7630-21-9 Phenyl-phosphonic acid mono-((1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl) ester 
• 67353-77-9 O-menthylchloro(phenyl)phosphonate 
• 35671-02-4 S_P-(-)-menthyl O-methyl phenylphosphate 
• 1256376-25-6 C₂₀H₃₅O₂PSi 
• 16934-93-3 (S_p)-Menthylmethylphenylphosphinate 
• 1256376-27-8 C₁₉H₃₁O₂P 
• 1256376-26-7 C₁₉H₂₉O₂P 
• 1228361-88-3 C₂₂H₂₉O₂PS 
• 1256376-29-0 C₃₄H₅₄N₂O₄P₂ 
• 1228361-56-5 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (R)-N-butyl-P-phenylphosphonamidate 
• 1228361-85-0 C₁₉H₃₁O₃P 
• 1228361-86-1 (-)-menthyl O-phenyl phenyl phosphonate 

Relevant academic research and scientific papers

Stereospecific halogenation of P(O)-H bonds with copper(II) chloride affording optically active Z1Z2P(O)Cl

A general and efficient method for the preparation of optically active Z1Z2P(O)Cl from the easily prepared optically active H-phosphinates and H-phosphine oxides was reported. H-Phosphinates and H-phosphine oxides react stereospecifi

SILICON-PHOSPHORUS ANALOGIES. PARTICIPATION OF EXTERNAL NUCLEOPHILES TO ACTIVATED PROCESSES OF RACEMIZATION AND HYDROLYSIS OF CHLOROPHOSPHONO DERIVATIVES

Kinetic and stereochemical studies show nucleophilic assistance by dimethylformamide (DMF), dimethylacetamide (DMA), hexamethylphosphotriamide (HMPT) and N-methylimidazole (NMI) in racemization and solvolysis of menthylchloro(phenyl)phosphonate, 1a, and O-ethylchloro(phenyl)thiophosphonate, 2.Similar orders of nucleophilic reactivity (Nu = NMI >> HMPT > DMF> DMA), and identical rate laws (vrac = k 2 and vH2O = k') are consistent with a common mechanism, governed by entropy (-60 u.e/= -40 u.e.).Analogies between reaction mechanisms at silicon and phosphorus are clearly evidenced.A two step process, involving rate-determining attack on a pentacoordinate complex is discussed.