67705-42-4

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• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 294-90-6 1,4,7,10-tetraazacyclododecan 
• 122-51-0 orthoformic acid triethyl ester 

Relevant academic research and scientific papers

A four-nitrogen [...] complex and its preparation method and application (by machine translation)

The invention of the formula (D) compound and its preparation method. In particular, the present invention of the formula (D) illustrated compound and its use in preparing test cloth qu gai. The preparation method of the raw materials are easy, low cost, simple process, is conducive to industrial production, and compared with the existing method, in the course of preparing resin consumption is remarkably reduced, and has good application prospect. (by machine translation)

Non-cytotoxic, bifunctional EuIII and TbIII luminescent macrocyclic complexes for luminescence resonant energy-transfer experiments

A new macrocyclic ligand, L3, has been synthesised, based on the cyclen framework grafted with three phenacyl light-harvesting groups and a C5-alkyl chain bearing a carboxylic acid function as a potential linker for biological material. Acidity

A PROCESS FOR THE PREPARATION OF 5H,9bH-2a, 4a,7,9a-OCTAHYDROTETRAAZACYCLOOCTA [cd] PENTALENE

A process for the preparation of 5H,9bH-2a,4a,7, 9a-octahydrotetraazacycloocta[cd]pentalene of formula (I) which comprises the reaction of 1,4,7,10-tetraazacyclododecane with triethyl orthoformate in the absence of solvent and in the presence of an acid catalyst.

A PROCESS FOR THE PREPARATION OF MACROCYCLIC CHELANTS AND THE CHELATES THEREOF WITH PARAMAGNETIC METAL IONS

A process for the preparation of complexes of macrocyclic chelants with paramagnetic metal trivalent ions of formula (XII) wherein R1, R2 and Me3+ are as described in the following, comprising: a) reaction of 1,4,7,10-tetraazacyclododecane with triethyl orthoformate to give 5H,9bH-2a,4a,7,9a-octahydrotetraazacycloocta[cd]pentalene; b) carboxymethylation reaction in water; c) hydrolysis reaction in basic conditions; d) alkylation according to known methods with an epoxide in water; e) complexation according to known methods carried out in water by addition of a paramagnetic metal salt; f) purification by diafiltration, final desalting of the aqueous solution on ion exchange resins and g) crystallization or recovery.

Gadolinium DO3A derivatives mimicking phospholipids; preparation and in vitro evaluation as pH responsive MRI contrast agents

A series of Gd-DO3A derivatives (8a-d) mimicking phospholipids have been prepared. Two of the complexes, Gd-HADB-DO3A (8a) and Gd-HADO-DO3A (8b), have been evaluated as pH responsive MRI contrast agents in vitro. The T1-relaxivity (r1/sub