67710-75-2

Basic information

• Product Name: (2R,6S,11R)-3-(cyclopropylmethyl)-11-methyl-6-(prop-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-8,11-diol
• Synonyms: 2,6-Methano-3-benzazocine-8,11-diol, 3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-11-methyl-6-(2-propenyl)-, (2R,6S,11R)-
• CAS NO: 67710-75-2
• Molecular Formula: C₂₀H₂₇NO₂
• Molecular Weight: 313.4339
• Mol File: 67710-75-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 460°C at 760 mmHg
• Flash Point: 227.1°C
• Density: 1.177g/cm³
• Vapor Pressure: 2.93E-09mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: (2R,6S,11R)-3-(cyclopropylmethyl)-11-methyl-6-(prop-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-8,11-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,6S,11R)-3-(cyclopropylmethyl)-11-methyl-6-(prop-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-8,11-diol(67710-75-2)
• EPA Substance Registry System: (2R,6S,11R)-3-(cyclopropylmethyl)-11-methyl-6-(prop-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-8,11-diol(67710-75-2)

Safety Data

• Hazardous Substances Data: 67710-75-2(Hazardous Substances Data)

Relevant articles and documents

5 Allyl 9 oxobenzomorphans. IV. Synthesis of 3 hydroxy 8 oxyisomorphinans, 5 allyl 9α hydroxy 6,7 benzomorphans, and related tetrahydrofuranobenzomorphans

A series of 3-hydroxy-8-oxyisomorphinans was synthesized from the corresponding 5-allyl-9β-hydroxy-6,7-benzomorphans via a hydroboration, oxidation, mesylation and cyclization sequence of reactions. Selective reduction of and methylmagnesium iodide addition to 5-allyl-2'-methoxy-2-methyl-9-oxo-6,7-benzomorphan gave the respective 9α-hydroxy-6,7-benzomorphans. These were transformed to a number of 2-substituted-5 allyl-2',9β-dihydroxy-6,7-benzomorphans and corresponding methyltetrahydrofurano analogs.