67715-13-3

Upstream product

• 1400277-52-2 C₁₁H₂₀N₂O*BrH 
• 95729-83-2 (S)-N-cyclohexyl-pyrrolidine-2-carboxamide 
• 108-91-8 cyclohexylamine 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 

Relevant academic research and scientific papers

Chiral amine catalyzed enantio- and diastereoselective Michael reaction in brine

Simple pyrrolidine-based chiral amines were synthesized and used for the Michael addition of different ketones to a variety of nitro-olefins in brine. The effect of different surfactants and acids on the yields and stereochemical outcome of the Michael ad

Asymmetric intramolecular aldol reaction mediated by (S)-N-substituted-N- (2-pyrrolidinylmethyl)amine to prepare Wieland-Miescher ketone

New or known N-substituted-N-(2-pyrrolidinylmethyl)amine derivatives bearing a variety of alkyl and aryl substituents were easily prepared from N-Boc-proline or N-Boc-N-(2-pyrrolidinylmethyl)amine. The enantioselectivity of the intramolecular asymmetric aldol reaction mediated by a combination of the amine derivative and TFA to prepare Wieland-Miescher ketone was examined. During the examination, optimal amount of TFA in the reaction was identified. The Japan Institute of Heterocyclic Chemistry.