67718-18-7Relevant academic research and scientific papers
Synthesis of functionalized furopyrazines as restricted dipeptidomimetics
Claerhout, Stijn,Sharma, Sweta,Sk?ld, Christian,Cavaluzzo, Claudia,Sandstr?m, Anja,Larhed, Mats,Thirumal, Meganathan,Parmar, Virinder S.,Van Der Eycken, Erik V.
, p. 3019 - 3029 (2012/05/31)
Herein, an efficient synthetic approach to a furopyrazine scaffold with four points of diversity, starting from 2(1H)-pyrazinones, with dipeptomimetic properties, is presented. R-groups corresponding to amino acid side chains were introduced during the 2(
Ag+-mediated synthesis of substituted furo[2,3-b]pyrazines
Ermolat'ev, Denis S.,Mehta, Vaibhav Pravinchandra,Van Der Eycken, Erik V.
, p. 3117 - 3122 (2008/09/19)
A highly efficient method for the preparation of trisubstituted furo[2,3-b]pyrazines has been developed. Sonogashira coupling reaction with the readily available 1-(4-methoxybenzyl)-3,5-dichloropyrazin-2(1H)-ones was followed by silver-catalyzed heteroann
