67727-97-3 Usage
Uses
Used in Pharmaceutical Industry:
ALPHA-MSH (11-13) ACETATE SALT is used as a potential therapeutic agent for the treatment of obesity due to its role in regulating appetite and metabolism.
Used in Dermatological Applications:
ALPHA-MSH (11-13) ACETATE SALT is used as a skin-protective agent for the treatment of certain skin conditions, leveraging its anti-inflammatory and skin-protective properties.
Used in Inflammatory Disease Treatment:
ALPHA-MSH (11-13) ACETATE SALT is used as an anti-inflammatory agent for the treatment of inflammatory diseases, given its potential to modulate inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 67727-97-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,7,2 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 67727-97:
(7*6)+(6*7)+(5*7)+(4*2)+(3*7)+(2*9)+(1*7)=173
173 % 10 = 3
So 67727-97-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H30N4O4/c1-10(2)13(16(23)24)19-14(21)12-7-5-9-20(12)15(22)11(18)6-3-4-8-17/h10-13H,3-9,17-18H2,1-2H3,(H,19,21)(H,23,24)/t11-,12-,13-/m0/s1
67727-97-3Relevant academic research and scientific papers
Masman, Marcelo F.,Rodriguez, Ana M.,Svetaz, Laura,Zacchino, Susana A.,Somlai, Csaba,Csizmadia, Imre G.,Penke, Botond,Enriz, Ricardo D.
, p. 7604 - 7614 (2006)
The synthesis, in vitro evaluation, and conformational study of His-Phe-Arg-Trp-NH2 and related derivatives acting as antifungal agents are reported. Among them, His-Phe-Arg-Trp-NH2 and His-Tyr-Arg-Trp-NH2 exhibited antifungal activity against Cryptococcus neoformans. Antifungal activity of these compounds appears to be closely related to the α-MSH effect. A conformational and electronic study allows us to propose a biologically relevant conformation for these tetrapeptides acting as antifungal agents. In addition, these theoretical calculations permit us to determine the minimal structural requirements to produce the antifungal response and may provide a guide for the design of compounds with this biological activity.
