677302-48-6

Usage

Type of compound

Heterocyclic compound

Core structure

Pyrrolopyridine

Substituent

Benzenesulfonyl group

Potential applications

Biological activities, building block in pharmaceuticals and agrochemicals, material science, and organic chemistry

Precautions

May pose health hazards if not properly managed and stored.

Upstream product

• 372077-49-1 1-benzenesulfonyl-5-methoxy-1H-pyrrolo[3,2-b]pyridine 
• 111795-99-4 2-(6-methoxy-3-nitropyridin-2-yl)acetonitrile 
• 17288-40-3 5-methoxy-4-aza-1H-indole 
• 5446-92-4 2-methoxy-5-nitropyridine 

Downstream Products

• 737003-25-7 1-benzenesulfonyl-5-(4-bromobutoxy)-1H-pyrrolo[3,2-b]pyridine 
• 737003-26-8 1-benzenesulfonyl-5-(5-bromopentyloxy)-1H-pyrrolo[3,2-b]pyridine 
• 737003-27-9 1-benzenesulfonyl-5-(6-bromohexyloxy)-1H-pyrrolo[3,2-b]pyridine 
• 1206181-57-8 trifluoromethanesulfonic acid 1-benzenesulfonyl-1H-pyrrolo[3,2-b]pyridin-5-yl ester 
• 737003-33-7 1,6-bis[(1-benzenesulfonyl-1H-pyrrolo[3,2-b]pyridin-5-yl)oxy]hexane 
• 737003-32-6 1,5-bis[(1-benzenesulfonyl-1H-pyrrolo[3,2-b]pyridin-5-yl)oxy]pentane 
• 737003-31-5 1,4-bis[(1-benzenesulfonyl-1H-pyrrolo[3,2-b]pyridin-5-yl)oxy]butane 

Relevant academic research and scientific papers

Convenient access to C-2 or C-5 substituted 4-azaindole derivatives

Functionalization at C-2 and C-5 of N-benzenesulfonyl-4-azaindole 1 was performed by lithiation reactions and original palladium-catalyzed chemistry. It led to very useful new substituted 4-azaindole derivatives in fair to high yields.

Preparation of 4-azaindole and 7-azaindole dimers with a bisalkoxyalkyl spacer in order to preferentially target melatonin MT1 receptors over melatonin MT2 receptors

Several 4-azaindole and 7-azaindole dimer analogues of melatonin with a bisalkoxyalkyl spacer between the position 5 of each heterocycle were synthetized. Our aim was to investigate the influence of the spacers length on the selectivity of such compounds