677304-75-5

Usage

Uses

Used in Pharmaceutical Research and Development:
6-Bromo-1,2-benzisothiazole-3-carboxylic acid is used as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique chemical structure allows for the development of new drug candidates with potential therapeutic applications.
Used in Chemical Research:
In the field of chemical research, 6-Bromo-1,2-benzisothiazole-3-carboxylic acid serves as a valuable compound for studying the properties and reactivity of benzisothiazole derivatives. This helps in understanding the fundamental chemistry of these compounds and exploring their potential applications in various industries.
Used in Material Science:
6-Bromo-1,2-benzisothiazole-3-carboxylic acid may also find applications in material science, particularly in the development of new materials with specific properties. Its unique structure can contribute to the creation of materials with tailored characteristics for use in various applications.
Used in Agrochemicals:
6-Bromo-1,2-benzisothiazole-3-carboxylic acid can be employed as a starting material or intermediate in the synthesis of agrochemicals, such as pesticides and herbicides. Its chemical properties may contribute to the development of effective and environmentally friendly agrochemical products.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 6-Bromo-1,2-benzisothiazole-3-carboxylic acid may be utilized for the synthesis of novel dyes and pigments with specific color properties and stability. Its aromatic and heterocyclic nature can contribute to the development of dyes with unique characteristics for various applications, such as textiles, plastics, and printing inks.

InChI:InChI=1/C8H4BrNO2S/c9-4-1-2-5-6(3-4)13-10-7(5)8(11)12/h1-3H,(H,11,12)

Upstream product

• 6320-01-0 3-Bromothiophenol 
• 947691-81-8 6-bromo-1,2-benzothiazole-3-carboxamide 

Downstream Products

• 858671-74-6 ethyl 6-bromobenzo[d]isothiazole-3-carboxylate 
• 932702-07-3 tert-butyl 6-bromo-benzo[d]isothiazole-3-carboxylate 

Relevant academic research and scientific papers

5H-CYCLOPENTA[D]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS

Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I).

CINNOLINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS

The present invention is directed tojcjnnoline compounds of formula (I) that are PDE 1 inhibitors, pharmaceutical compositions containing such compounds and process for preparing such compounds. This invention is also directed to methods of treating diseases treatable by inhibition of PDElO enzyme, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.

CINNOLINE AND QUINAZOLINE DERIVATES AS PHOSPHODIESTERASE 10 INHIBITORS

The present invention is directed to cinnoline and quinazoline compounds of formula (I) that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.

COMPOUNDS AND METHODS FOR MODULATING FXR

Compounds of formula. wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.

1 H-INDAZOLES, BENZOTHIAZOLES, 1,2-BENZOISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND CHROMONES AND PREPARATION AND USES THEREOF

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of -disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

COMPOUNDS AND METHODS FOR MODULATING FXR

Compounds of formula (I) wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and related diseases.

Indoles, 1h-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.