67737-80-8Relevant academic research and scientific papers
Biotransformation of linalool to furanoid and pyranoid linalool oxides by Aspergillus niger
Demyttenaere, Jan C.R.,Willemen, Hendra M.
, p. 1029 - 1036 (1998)
Biotransformation of (±)-linalool with submerged shaking cultures of Aspergillus niger, particularly A. niger ATCC 9142, yielded a mixture of cis- and trans-furanoid linalool oxide (yield 15-24%) and cis- and trans-pyranoid linalool oxide (yield 5-9%). Biotransformation of (R)-(-)-linalool with the same strain yielded almost pure trans-furanoid and trans-pyranoid linalool oxide (ee > 95). These conversions were purely biocatalytic, since in acidified water (pH 3.5) almost 50% linalool was recovered unchanged, the rest was lost by evaporation. The biotransformation was also carried out with growing surface cultures.
REGIOSPECIFIC HYDROXYLATION OF ACYCLIC MONOTERPENE ALCOHOLS BY ASPERGILLUS NIGER
Madyastha, Madhava K.,Krishna Murthy, N. S. R.
, p. 579 - 580 (2007/10/02)
Aspergillus niger was shown to carry out the regiospecific hydroxylation of acyclic monoterpene alcohols.
Alkylation du linalol sur les carbones C8 (et C6)
Cuvigny, Therese,Julia, Marc,Rolando, Christian
, p. 9 - 28 (2007/10/02)
Metallation of linalool α to the distal double bond with strong bases is described.The corresponding carbanions have been alkylated or oxidized to give mixtures of products resulting from attack at both carbon 8 (major product) and carbon 6 (minor product).
