67743-63-9

Upstream product

• 64064-25-1 2-Amino-5-(phenylthio)pyridin 

Downstream Products

• 139585-62-9 5-Benzenesulfonyl-2-(phenyl-trimethylsilanyloxy-methyl)-pyridine 
• 139585-67-4 5-(Phenylsulfonyl)-2-(trimethylsilyl)pyridin 
• 139585-68-5 5-Phenylsulfanyl-2-trimethylsilanyl-pyridine 

Relevant academic research and scientific papers

On the Mechanism of the Carbodesilylation of 4- or 5-Substituted 2-(Trimethylsilyl)pyridines

An "ylide mechanism" is proposed for the carbodesilylation of 2-(trimethylsilyl)pyridines with benzaldehyde.In contrast, 3- and 4-(trimethylsilyl)pyridines, react only in the presence of a base catalyst via pyridyl anions with electrophiles.The rates of the uncatalyzed carbodesilylation reactions of 4-substituted 2-(trimethylsilyl)pyridines 2 with benzaldehyde correlate very well with the resonance parameters of the substituents ?0R, whereas the rates of 5-substituted 2-(trimethylsilyl)pyridines 7 correlate with the inductive substituent parameters ?1 in the Taft equation.This is to our knowledge the first direct determination of the resonance parameters ?0R.Key Words: Pyridines, substituted 2-(trimethylsilyl)-, synthesis of, carbodesilylation of / Carbodesilylation / Rate constants

Process for the preparation of imidazo [1,2-a] pyridines

Processes are described for the preparation of 2-(methoxycarbonylamino)-6-(phenylsulfinyl) imidazo [1,2-a] pyridine, which is an active anthelmintic agent. The process involves the treatment of a 5-phenylsulfinyl pyridine substituted at the 2-position wit