67743-67-3

Upstream product

• 18108-77-5 5-phenylsulfanylpyridin-2(1H)-one 
• 3111-52-2 potassium thiophenolate 
• 13466-38-1 5-bromopyridin-2(1H)-one 
• 64064-25-1 2-Amino-5-(phenylthio)pyridin 
• 108-98-5 thiophenol 
• 69045-79-0 2-choro-5-iodopyridine 
• 67743-62-8 2-chloro-5-(phenylsulfanyl)pyridine 

Downstream Products

• 877866-86-9 C₁₉H₁₃NSOF₂ 
• 64064-54-6 methyl 6-(phenylsulfinyl)imidazo<1,2-a>pyridine-2-carbamate 

Relevant academic research and scientific papers

PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE

The present invention provides, in part, novel small molecule inhibitors of PHD, having a structure according to Formula (A), and sub-formulas thereof: or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for treatment of diseases including heart ( e.g. ischemic heart disease, congestive heart failure, and valvular heart disease), lung (e.g., acute lung injury, pulmonary hypertension, pulmonary fibrosis, and chronic obstructive pulmonary disease), liver (e.g. acute liver failure and liver fibrosis and cirrhosis), and kidney (e.g. acute kidney injury and chronic kidney disease) disease.

2,5-Disubstituted pyridines: The discovery of a novel series of 5-HT2A ligands

This report describes the effect of replacing the central basic amine present in many known 5-HT2A ligands with an aromatic residue. We targeted the isomeric phenethylpyridines 2 and 3 and these compounds proved to be excellent leads, possessin

Process for the preparation of imidazo [1,2-a] pyridines

Processes are described for the preparation of 2-(methoxycarbonylamino)-6-(phenylsulfinyl) imidazo [1,2-a] pyridine, which is an active anthelmintic agent. The process involves the treatment of a 5-phenylsulfinyl pyridine substituted at the 2-position wit