67761-65-3Relevant academic research and scientific papers
Preparation of rearranged allylic isocyanates from the reaction of allylic alcohols with 1-Cyano-4-dimethylaminopyridinium bromide
Baidilov, Daler,Makarova, Mariia,Rycek, Lukas,Hudlicky, Tomas
, p. 4606 - 4610 (2019/02/01)
A shorter and less costly alternative to Ichikawa's [1,3]-Transposition protocol for cyanates to isocyanates is described.
Synthesis of manzacidin A and C: Efficient construction of quaternary carbon stereocenters bearing nitrogen substituents
Ichikawa, Yoshiyasu,Okumura, Ken,Matsuda, Yasunori,Hasegawa, Tomoyuki,Nakamura, Mitsuhiro,Fujimoto, Aya,Masuda, Toshiya,Nakano, Keiji,Kotsuki, Hiyoshizo
, p. 614 - 622 (2012/02/05)
An efficient synthetic method for stereoselective construction of asymmetric quaternary carbon stereocenters, bearing nitrogen in the form of Boc-protected allyl amines, has been developed. This methodology is employed in the synthesis of marine alkaloids
One-pot transformation of trichloroacetamide into readily deprotectable carbamates
Nishikawa, Toshio,Urabe, Daisuke,Tomita, Miho,Tsujimoto, Takashi,Iwabuchi, Tomoko,Isobe, Minoru
, p. 3263 - 3265 (2007/10/03)
A trichloroacetamide group was converted to an isocyanate, which was in situ captured by a variety of alcohols in the presence of CuCl and n-BuN 4Cl to afford the corresponding carbamates. The scope and limitation of this transformation are als
A new synthetic method for the preparation of amino sugars through an allyl cyanate-to-isocyanate rearrangement
Ichikawa, Yoshiyasu,Osada, Masafumi,Ohtani, Ikuko I.,Isobe, Minoru
, p. 1449 - 1455 (2007/10/03)
A new approach for the synthesis of amino sugars using an allyl cyanate-to-isocyanate rearrangement has been developed. The key feature in this method involves introduction of the nitrogen substituent into the pyranose framework by [3,3] sigmatropic rearrangement of an allyl cyanate. Subsequent functionalization of the allylamine moiety by either hydroxylation or cyclofunctionalization completes the synthesis of two amino sugars, D-perosamine and D-vicenisamine.
