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1-cyclohexyl-iMidazole, with the chemical formula C9H14N2, is an organic heterocyclic compound that features both a cyclohexane and an imidazole ring. It is widely recognized for its role as a reagent in organic synthesis and is valued for its anti-fungal properties, which make it a promising candidate in pharmaceutical applications, particularly in the development of antifungal drugs. Moreover, its potential as an anti-cancer agent and a bacteriostatic substance has been the subject of research, while its utility as a corrosion inhibitor and an intermediate in chemical production further underscores its versatility.

67768-61-0

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67768-61-0 Usage

Uses

Used in Pharmaceutical Applications:
1-cyclohexyl-iMidazole is used as an active pharmaceutical ingredient for its anti-fungal properties, targeting the development of antifungal drugs to combat fungal infections.
Used in Organic Synthesis:
As a reagent, 1-cyclohexyl-iMidazole is used in various organic synthesis processes, facilitating the creation of a range of chemical compounds.
Used in Corrosion Inhibition:
1-cyclohexyl-iMidazole is used as a corrosion inhibitor, helping to protect materials from degradation due to environmental factors.
Used in Chemical Production:
1-cyclohexyl-iMidazole serves as an intermediate in the production of various chemicals, contributing to the synthesis of a multitude of compounds.
Used in Anticancer Research:
1-cyclohexyl-iMidazole is used as a subject of research for its potential anti-cancer properties, with studies exploring its effects on inhibiting the growth of cancer cells.
Used in Bacterial Growth Inhibition:
It is also used in research to study its ability to inhibit the growth of certain bacteria, which could lead to new antimicrobial agents.
It is crucial to handle 1-cyclohexyl-iMidazole with care due to its potential harmful effects if ingested or if it comes into contact with the skin or eyes.

Check Digit Verification of cas no

The CAS Registry Mumber 67768-61-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,7,6 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 67768-61:
(7*6)+(6*7)+(5*7)+(4*6)+(3*8)+(2*6)+(1*1)=180
180 % 10 = 0
So 67768-61-0 is a valid CAS Registry Number.

67768-61-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-cyclohexylimidazole

1.2 Other means of identification

Product number -
Other names 1-cyclohexyl-1H-imidazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:67768-61-0 SDS

67768-61-0Relevant academic research and scientific papers

Synthesis and structure of palladium(II) complexes supported by bis-NHC pincer ligands for the electrochemical activation of CO2

Andrade, Gabriel A.,DiMeglio, John L.,Guardino, Eric T.,Yap, Glenn P.A.,Rosenthal, Joel

, p. 134 - 143 (2017)

A series of bis-NHC pincer complexes of palladium(II) have been prepared and characterized. These pyridyl-spaced dicarbene complexes ([(PDCR)Pd(MeCN)](PF6)2) were synthesized with substituents of varying steric bulk at the

Isoprene as lithiation mediator: Synthesis of 2-substituted 1-alkylimidazole derivatives

Martinez, Regina,Torregrosa, Rosario,Pastor, Isidro M.,Yus, Miguel

experimental part, p. 2630 - 2638 (2012/09/07)

The lithiation of different imidazoles bearing a primary (i.e., butyl, pentyl, dodecyl) or secondary (i.e., cyclohexyl, 1-methylheptyl) alkyl substituent on the nitrogen has been successfully achieved by means of an isoprene-mediated protocol. The subsequent reaction of the 2-lithioimidazole intermediates with different electrophiles leads to the formation of interesting 1,2-disubstituted imidazoles. Georg Thieme Verlag Stuttgart · New York.

Isoprene-mediated lithiation of 1-alkylimidazoles: Chiral induction of the alkyl substituent

Pastor, Isidro M.,Torregrosa, Rosario,Yus, Miguel

experimental part, p. 373 - 376 (2011/04/12)

The isoprene-mediated lithiation of imidazoles bearing a secondary alkyl substituent at the nitrogen (7, 8 and 13) and the subsequent nucleophilic addition to different electrophiles allows the preparation of the corresponding 2-functionalized imidazoles

Cycloalkyl heterocycles for treating Hepatitis C virus

-

Page/Page column 37, (2010/02/11)

Compounds of Formula I are disclosed which inhibit hepatitis C NS5B RNA-dependent RNA polymerase and are useful for treating hepatitis C. Compositions and methods of using these compounds are also disclosed.

Copper carbenoid mediated N-alkylation of imidazoles and its use in a novel synthesis of bifonazole

Cuevas-Ya?ez, Erick,Serrano, Juan Manuel,Huerta, Gloria,Muchowski, Joseph M.,Cruz-Almanza, Raymundo

, p. 9391 - 9396 (2007/10/03)

1H-Imidazoles are readily N-alkylated by a Cu(acac)2 mediated reaction with α-diazocarbonyl compounds or with diazoalkanes generated in situ from the corresponding p-toluensulfonyl hydrazones. The antifungal agent bifonazole was prepared by the latter method. Graphical Abstract.

Optically active iridium imidazol-2-ylidene-oxazoline complexes: Preparation and use in asymmetric hydrogenation of arylalkenes

Perry, Marc C.,Cui, Xiuhua,Powell, Mark T.,Hou, Duen-Ren,Reibenspies, Joseph H.,Burgess, Kevin

, p. 113 - 123 (2007/10/03)

This work explores the potential of iridium complexes of the N-heterocyclic carbene oxazoline ligands 1 in asymmetric hydrogenations of arylalkenes. The accessible carbene precursors, imidazolium salts 2, and robust iridium complexes 5 facilitated a disco

Synthesis of 1-alkylimidazoles

Gridnev,Mihaltseva

, p. 1547 - 1555 (2007/10/02)

A mechanistic investigation of the synthesis of imidazole and 1- alkylimidazoles has led to an improved synthesis starting from glyoxal, formaldehyde and alkylammonium chlorides.

3-Imidazolium cephalosporin derivatives

-

, (2008/06/13)

A cephalosporin compound substituted by imidazolium ring in 3-position of cephem having the following formula (I), and pharmaceutically acceptable salt thereof, STR1 wherein R1 is an organic residue known in β-lactam antibiotics, R2 is hydrogen atom or methoxy, n is 0 or 1, A is a nitrogen-containing group constituting imidazolium ring, is useful as an agent for preventing and treating bacterial infections.

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