67768-61-0Relevant academic research and scientific papers
Synthesis and structure of palladium(II) complexes supported by bis-NHC pincer ligands for the electrochemical activation of CO2
Andrade, Gabriel A.,DiMeglio, John L.,Guardino, Eric T.,Yap, Glenn P.A.,Rosenthal, Joel
, p. 134 - 143 (2017)
A series of bis-NHC pincer complexes of palladium(II) have been prepared and characterized. These pyridyl-spaced dicarbene complexes ([(PDCR)Pd(MeCN)](PF6)2) were synthesized with substituents of varying steric bulk at the
Isoprene as lithiation mediator: Synthesis of 2-substituted 1-alkylimidazole derivatives
Martinez, Regina,Torregrosa, Rosario,Pastor, Isidro M.,Yus, Miguel
experimental part, p. 2630 - 2638 (2012/09/07)
The lithiation of different imidazoles bearing a primary (i.e., butyl, pentyl, dodecyl) or secondary (i.e., cyclohexyl, 1-methylheptyl) alkyl substituent on the nitrogen has been successfully achieved by means of an isoprene-mediated protocol. The subsequent reaction of the 2-lithioimidazole intermediates with different electrophiles leads to the formation of interesting 1,2-disubstituted imidazoles. Georg Thieme Verlag Stuttgart · New York.
Isoprene-mediated lithiation of 1-alkylimidazoles: Chiral induction of the alkyl substituent
Pastor, Isidro M.,Torregrosa, Rosario,Yus, Miguel
experimental part, p. 373 - 376 (2011/04/12)
The isoprene-mediated lithiation of imidazoles bearing a secondary alkyl substituent at the nitrogen (7, 8 and 13) and the subsequent nucleophilic addition to different electrophiles allows the preparation of the corresponding 2-functionalized imidazoles
Cycloalkyl heterocycles for treating Hepatitis C virus
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Page/Page column 37, (2010/02/11)
Compounds of Formula I are disclosed which inhibit hepatitis C NS5B RNA-dependent RNA polymerase and are useful for treating hepatitis C. Compositions and methods of using these compounds are also disclosed.
Copper carbenoid mediated N-alkylation of imidazoles and its use in a novel synthesis of bifonazole
Cuevas-Ya?ez, Erick,Serrano, Juan Manuel,Huerta, Gloria,Muchowski, Joseph M.,Cruz-Almanza, Raymundo
, p. 9391 - 9396 (2007/10/03)
1H-Imidazoles are readily N-alkylated by a Cu(acac)2 mediated reaction with α-diazocarbonyl compounds or with diazoalkanes generated in situ from the corresponding p-toluensulfonyl hydrazones. The antifungal agent bifonazole was prepared by the latter method. Graphical Abstract.
Optically active iridium imidazol-2-ylidene-oxazoline complexes: Preparation and use in asymmetric hydrogenation of arylalkenes
Perry, Marc C.,Cui, Xiuhua,Powell, Mark T.,Hou, Duen-Ren,Reibenspies, Joseph H.,Burgess, Kevin
, p. 113 - 123 (2007/10/03)
This work explores the potential of iridium complexes of the N-heterocyclic carbene oxazoline ligands 1 in asymmetric hydrogenations of arylalkenes. The accessible carbene precursors, imidazolium salts 2, and robust iridium complexes 5 facilitated a disco
Synthesis of 1-alkylimidazoles
Gridnev,Mihaltseva
, p. 1547 - 1555 (2007/10/02)
A mechanistic investigation of the synthesis of imidazole and 1- alkylimidazoles has led to an improved synthesis starting from glyoxal, formaldehyde and alkylammonium chlorides.
3-Imidazolium cephalosporin derivatives
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, (2008/06/13)
A cephalosporin compound substituted by imidazolium ring in 3-position of cephem having the following formula (I), and pharmaceutically acceptable salt thereof, STR1 wherein R1 is an organic residue known in β-lactam antibiotics, R2 is hydrogen atom or methoxy, n is 0 or 1, A is a nitrogen-containing group constituting imidazolium ring, is useful as an agent for preventing and treating bacterial infections.
