677709-60-3Relevant academic research and scientific papers
A Convenient Synthesis of a Selective Gelatinase Inhibitor as an Antimetastatic Agent
Lim, In Taek,Brown, Stephen,Mobashery, Shahriar
, p. 3572 - 3573 (2004)
Compound 1, 2-(4-phenoxyphenylsulfonylmethyl)thiirane, is a potent and selective inhibitor for human gelatinases (J. Am. Chem. Soc. 2000, 122, 6799-6800), enzymes implicated in a number of diseases, including cancer. This compound is showing excellent pro
INHIBITORS OF MATRIX METALLOPROTEINASES
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Page/Page column 93-94, (2008/06/13)
The present invention provides novel compounds of formulas I-IX, as described herein. Also provided are compositions of compounds of formulas I-IX, methods of making compounds of formulas I-IX, and methods of using compounds of formulas I-IX. The compounds of the invention can be used to inhibit matrix metalloproteinases, and are useful to treat conditions and diseases associated therewith.
