677709-83-0Relevant academic research and scientific papers
Azo Group-Assisted Nucleophilic Aromatic Substitutions in Haloarene Derivatives: Preparation of Substituted 1-Iodo-2,6-bispropylthiobenzenes
Jason, T. Manka,McKenzie, Virginia C.,Kaszynski, Piotr
, p. 1967 - 1971 (2007/10/03)
Aryldiazo substituents were usfed in nucleophilic aromatic substitution reactions of halogens. The Ph-N=N- group activates ortho fluorine atoms toward alkylthiolation under mild conditions. In contrast, the Me2N-C6H4-N=N- group has virtually no activation effect in nucleophilic aromatic substitution, and serves as a "neutral" mask for the amino group. The Ph-N=N- group was efficiently introduced by diazo coupling of aryllithium with dry PhN2(1+)BF4(1-) salt.
