67772-76-3Relevant articles and documents
Highly efficient synthesis of (+)-bromoxone, (+)-epiepoxydon and (+)-epiepoformin
Jin, Mng Yu,Hwang, Geum-Sook,Chae, Hee H,Jung, Sun Hee,Ryu, Do Hyun
scheme or table, p. 727 - 730 (2010/08/19)
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Total synthesis of (+)-epiepoformin, (+)-epiepoxydon and (+)-bromoxone employing a useful chiral building block, ethyl (1R,2S)-5,5-ethylenedioxy-2-hydroxycyclohexanecarboxylate
Tachihara, Toru,Kitahara, Takeshi
, p. 1773 - 1780 (2007/10/03)
Enantioselective total synthesis of (+)-epiepoformin 1, (+)-epiepoxydon 2 and (+)-bromoxone 3 using a chiral building block, ethyl (1R,2S)-5,5-ethylenedioxy-2-hydroxycyclo- hexanecarboxylate 6, is described. Since the synthesis afforded intermediates 18, 2 and 25, it accomplished a formal synthesis of (-)-theobroxide 19, (-)-phyllostine 22, (+)-herveynone 27 and (-)-asperpentyn 28. The usefulness of 6 for the synthesis of natural epoxycyclohexene derivatives was demonstrated.
Stereo- and enantio-controlled synthesis of two naturally occurring polyoxygenated cyclohexenemethanols, (+)-epiepoxydon and (-)-phyllostine, via catalytic asymmetrization of a meso substrate
Kamikubo, Takashi,Hiroya, Kou,Ogasawara, Kunio
, p. 499 - 502 (2007/10/02)
Two naturally occurring polyoxygenated cyclohexenemethanols, (+)-epiepoxydon and (-)-phyllostine, have been first synthesized in stereo- and enantio-controlled manner using a chiral cyclohexadienol synthon prepared by catalytic asymmetrization of a meso substrate. The synthesis has verified the proposed absolute structures of these natural products which have been deduced by CD measurements.
