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1-Piperazinecarboxylic acid, 4-[[4-[2-[(2-acetyl-5-benzofuranyl)amino]-4-pyrimidinyl]phenyl]sulfonyl]-, 1,1-dimethylethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

677753-04-7

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677753-04-7 Usage

Chemical Classification

Ester derivative of piperazinecarboxylic acid.

Structural Relation

Related to certain drugs used in cancer treatment and other diseases.

Potential Therapeutic Properties

Suggests potential as a therapeutic agent in the treatment of various conditions.

Molecular Targets

May act on specific molecular targets in the body.

Further Research and Development

Could lead to new treatments for medical conditions and diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 677753-04-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,7,7,5 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 677753-04:
(8*6)+(7*7)+(6*7)+(5*7)+(4*5)+(3*3)+(2*0)+(1*4)=207
207 % 10 = 7
So 677753-04-7 is a valid CAS Registry Number.

677753-04-7Downstream Products

677753-04-7Relevant academic research and scientific papers

A novel series of potent and selective IKK2 inhibitors

Bingham, Alistair H.,Davenport, Richard J.,Gowers, Lewis,Knight, Roland L.,Lowe, Christopher,Owen, David A.,Parry, David M.,Pitt, Will R.

, p. 409 - 412 (2007/10/03)

A novel series of aminopyrimidine IKK2 inhibitors have been developed which show excellent in vitro inhibition of this enzyme and good selectivity over the IKK1 isoform. The relative potency and selectivity of these compounds has been rationalized using QSAR and structure-based modelling.

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