677757-33-4 Usage
Uses
Used in Pharmaceutical Applications:
(1S,2S,3R,4R)-(+)-3-AMINOBICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE is used as a building block in organic synthesis for the development of pharmaceutical compounds due to its unique structure and biological activity.
Used in Chemical Biology:
(1S,2S,3R,4R)-(+)-3-AMINOBICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE is used as a ligand in metal-catalyzed reactions for the study of its properties and potential applications in chemical biology.
Used in Medicinal Chemistry:
(1S,2S,3R,4R)-(+)-3-AMINOBICYCLO[2.2.1]HEPT-5-ENE-2-CARBOXYLIC ACID HYDROCHLORIDE is used as a subject of interest in the field of medicinal chemistry for its potential pharmaceutical applications and unique structure.
Check Digit Verification of cas no
The CAS Registry Mumber 677757-33-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,7,7,5 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 677757-33:
(8*6)+(7*7)+(6*7)+(5*7)+(4*5)+(3*7)+(2*3)+(1*3)=224
224 % 10 = 4
So 677757-33-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO2.ClH/c9-7-5-2-1-4(3-5)6(7)8(10)11;/h1-2,4-7H,3,9H2,(H,10,11);1H/t4-,5+,6+,7-;/m1./s1
677757-33-4Relevant academic research and scientific papers
Forro, Eniko,Fueloep, Ferenc
, p. 573 - 575 (2004)
1,4-Ethyl- and 1,4-ethylene-bridged cispentacin enantiomers 1a, 1c and 2a, 2c were prepared through the lipase-catalyzed enantioselective ring opening of racemic exo-3-azatricyclo[4.2.1.02.5]nonan-4-one, (±)-1, and exo-3-azatricyclo[4.2.1.02.5]non-7-en-4-one, (±)-2. High enantioselectivity (E >200) was observed when the Lipolase-catalyzed reactions were performed with 1equiv of H2O in diisopropyl ether at 70°C. The resolved β-amino acids 1a and 2a (yield 46%) and β-lactams 1b and 2b (yield≥40%) could be easily separated. The ring opening of lactam enantiomers with 18% HCl afforded the corresponding β-amino acid hydrochloride enantiomers (ee ≥98%).
