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Usage

Uses

Used in Pharmaceutical Industry:
3-Pyridinecarboxylicacid,1,6-dihydro-1,5-dimethyl-6-oxo-(9CI) is used as a pharmaceutical intermediate for the synthesis of certain drugs and agrochemicals. Its unique structure and properties make it a valuable component in the development of new medications and chemical products.
Used in Bacterial Metabolism:
In the field of microbiology, 3-Pyridinecarboxylicacid,1,6-dihydro-1,5-dimethyl-6-oxo-(9CI) plays a significant role as an intermediate in the bacterial degradation of the herbicide picloram. This application aids in understanding the metabolic pathways of bacteria and their ability to break down harmful substances in the environment.
Used in Bacterial Growth and Survival:
3-Pyridinecarboxylicacid,1,6-dihydro-1,5-dimethyl-6-oxo-(9CI) is essential for the growth and survival of certain bacteria, as it serves as a key precursor in the biosynthesis of NAD from tryptophan. This makes it an important compound in studying bacterial metabolism and the development of new antibiotics or other treatments targeting specific bacterial species.

Upstream product

• 51417-13-1 5-bromo-1,3-dimethyl-1,2-dihydropyridin-2-one 
• 89488-30-2 5-bromo-2-hydroxy-3-methyl pyridine 

Relevant academic research and scientific papers

COMBINATION TREATMENT OF ACUTE MYELOID LEUKEMIA

The present invention relates to the use of volasertib, or a pharmaceutically acceptable salt thereof or a hydrate thereof, in combination with a BET inhibitor, or a pharmaceutically acceptable salt thereof or a hydrate thereof for treating patients suffering from acute myeloid leukemia (AML).

PYRIDINONES

The present invention encompasses compounds of general formula (I) wherein the groups R1 to R3 and X1 through X6 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.

PYRIDINONES

The present invention encompasses compounds of general formula (I) wherein the groups R1 to R3 and X1 through X6 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.

BENZIMIDAZOLE DERIVATIVES

The present invention encompasses compounds of the general formula (I) wherein the groups A, R1 to R2 and X have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.

N-substituted-2-oxodihydropyridine derivatives

A compound of the formula (I): (wherein Ar1 and Ar2 are independently aryl or heteroaryl, any of which is optionally substituted by a substituent selected from the group consisting of cyano, halogen, nitro, lower alkyl, halo-lower al