67801-22-3 Usage
General Description
2,2-Dimethyl-6-methylenecyclohexaneacetonitrile is a chemical compound with the molecular formula C11H17N. It is a colorless liquid with a molecular weight of 167.25 g/mol. 2,2-Dimethyl-6-methylenecyclohexaneacetonitrile is used as a reagent in organic synthesis and as an intermediate in the production of pharmaceuticals and other fine chemicals. It is important to handle this compound with care, as it is flammable and may cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Additionally, 2,2-Dimethyl-6-methylenecyclohexaneacetonitrile should be stored in a cool, dry, well-ventilated area away from sources of ignition and incompatible substances.
Check Digit Verification of cas no
The CAS Registry Mumber 67801-22-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,8,0 and 1 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 67801-22:
(7*6)+(6*7)+(5*8)+(4*0)+(3*1)+(2*2)+(1*2)=133
133 % 10 = 3
So 67801-22-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H17N/c1-9-5-4-7-11(2,3)10(9)6-8-12/h10H,1,4-7H2,2-3H3
67801-22-3Relevant articles and documents
A general strategy for the stereoselective synthesis of the furanosesquiterpenes structurally related to pallescensins 1-2
Serra, Stefano
, (2019/05/24)
Here, we describe a general stereoselective synthesis of the marine furanosesquiterpenes structurally related to pallescensins 1-2. The stereoisomeric forms of the pallescensin 1, pallescensin 2, and dihydropallescensin 2 were obtained in high chemical and isomeric purity, whereas isomicrocionin-3 was synthesized for the first time. The sesquiterpene framework was built up by means of the coupling of the C10 cyclogeranyl moiety with the C5 3-(methylene)furan moiety. The key steps of our synthetic procedure are the stereoselective synthesis of four cyclogeraniol isomers, their conversion into the corresponding cyclogeranylsulfonylbenzene derivatives, their alkylation with 3-(chloromethyl)furan, and the final reductive cleavage of the phenylsulfonyl functional group to afford the whole sesquiterpene framework. The enantioselective synthesis of the α-, 3,4-dehydro-γ- and γ-cyclogeraniol isomers was performed using both a lipase-mediated resolution procedure and different regioselective chemical transformations.
