67804-93-7

Usage

Heterocyclic compound

Contains a pyrimidine ring

Substituents

Phenyl and trifluoromethyl groups

Pharmaceutical use

Building block for the synthesis of biologically active molecules

Pharmacological activities

Potential anticonvulsant and anxiolytic properties

Potential therapeutic applications

Treatment of neurological disorders and cancer

Unique chemical structure

Valuable for further research and development in medicinal chemistry.

Upstream product

• 5329-33-9 o-methylisourea hydrochloride 
• 6048-29-9 triphenylphenacylphosphonium bromide 
• 326-06-7 1-Phenyl-4,4,4-trifluorobutane-1,3-dione 
• 57-13-6 urea 

Downstream Products

• 503146-00-7 2-chloro-4-phenyl-6-(trifluoromethyl)pyrimidine 

Relevant academic research and scientific papers

Fluorinated β-diketo phosphorus ylides: Their cyclocondensation with amidines affording 4-trifluoromethyl- And 4-perfluoroalkyl-substituted pyrimidines

A study is presented for the syntheses of a series of 4-trifluoromethyl- and 4-perfluoroalkyl-substituted pyrimidines from the reaction of trifluoromethyl or perfluoroalkyl β-diketo phosphorus ylides (Ph3P=C(CORF)COR) with amidine hydrochloride.

THIAZOLIDINE DERIVATIVE AND MEDICINAL USE THEREOF

A thiazolidine derivative represented by the formula (I) wherein each symbol is as defined in the specification, and a pharmaceutically acceptable salt thereof exhibit a potent DPP-IV inhibitory activity, and can be provided as an agent for the prophylaxis or treatment of diabetes, an agent for the prophylaxis or treatment of obesity and the like.