67805-68-9 Usage
Uses
Used in Pharmaceutical Industry:
2(1H)-Quinolinone, 8-bromo-3,4-dihydrois used as a key component in various pharmaceutical drugs for its biological activities and practicality. Its presence in the structure of these drugs contributes to their therapeutic effects and potential applications in treating different medical conditions.
Used in Drug Synthesis:
2(1H)-Quinolinone, 8-bromo-3,4-dihydrois utilized in the synthesis of new drugs, where its unique structure and properties can be leveraged to develop novel therapeutic agents with improved efficacy and safety profiles.
Used in Scientific Research:
2(1H)-Quinolinone, 8-bromo-3,4-dihydrois employed in scientific research to explore its potential applications and understand its interactions with biological systems. This can lead to the discovery of new drug targets and the development of innovative therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 67805-68-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,8,0 and 5 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 67805-68:
(7*6)+(6*7)+(5*8)+(4*0)+(3*5)+(2*6)+(1*8)=159
159 % 10 = 9
So 67805-68-9 is a valid CAS Registry Number.
67805-68-9Relevant academic research and scientific papers
Visible-Light Induced C(sp2)?H Amidation with an Aryl–Alkyl σ-Bond Relocation via Redox-Neutral Radical–Polar Crossover
Chang, Sukbok,Jeong, Jiwoo,Jung, Hoimin,Keum, Hyeyun,Kim, Dongwook
supporting information, p. 25235 - 25240 (2021/10/25)
We report an approach for the intramolecular C(sp2)?H amidation of N-acyloxyamides under photoredox conditions to produce δ-benzolactams with an aryl-alkyl σ-bond relocation. Computational studies on the designed reductive single electron transfer strategy led us to identify N-[3,5-bis(trifluoromethyl)benzoyl] group as the most effective amidyl radical precursor. Upon the formation of an azaspirocyclic radical intermediate by the selective ipso-addition with outcompeting an ortho-attack, radical–polar crossover was then rationalized to lead to the rearomative ring-expansion with preferential C?C bond migration.
