6781-42-6

Basic information

• Product Name: 1,3-DIACETYLBENZENE
• Synonyms: Ethanone, 1,1'-(1,3-phenylene)bis-;1,3-DIACETYLBENZENE;M-DIACETYLBENZENE;M-ACETYL ACETOPHENONE;benzene-1,3-bis(acetyl);1,3-Diacetylbenzene,97%;1,1'-m-Phenylenebisethanone;1,3-Diacetylbenzene,99%
• CAS NO: 6781-42-6
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.19
• EINECS: 229-842-9
• Product Categories: Aromatic Ketones (substituted);C10;Carbonyl Compounds;Ketones;Furans ,Coumarins
• Mol File: 6781-42-6.mol
• Article Data: 26

Chemical Properties

• Melting Point: 28-32 °C(lit.)
• Boiling Point: 150-155 °C15 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Clear slightly yellow/Liquid After Melting
• Density: 1.0613 (rough estimate)
• Vapor Pressure: 0.00382mmHg at 25°C
• Refractive Index: 1.5485-1.5505
• Storage Temp.: 2-8°C
• Solubility: Soluble in ethanol, benzene, chloroform.
• BRN: 2042511
• CAS DataBase Reference: 1,3-DIACETYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-DIACETYLBENZENE(6781-42-6)
• EPA Substance Registry System: 1,3-DIACETYLBENZENE(6781-42-6)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 6781-42-6(Hazardous Substances Data)

Usage

Uses

1,3-Diacetylbenzene was used in the preparation of polyhydroxylated analogs. It is an important raw material and intermediates in organic synthesis.

General Description

1,3-Diacetylbenzene is an δ-diketone. It induces neuropathological changes in the rodent central and peripheral nervous systems.

InChI:InChI=1/C10H10O2/c1-7(11)9-4-3-5-10(6-9)8(2)12/h3-6H,1-2H3

Upstream product

• 141-93-5 m-diethylbenzene 
• 99-03-6 1-(3-aminophenyl)ethanone 
• 431-03-8 dimethylglyoxal 
• 108-57-6 1,3-divinylbenzene 
• 75-16-1 methylmagnesium bromide 
• 60-35-5 acetamide 
• 98-86-2 acetophenone 
• 1785-61-1 1,3-diethynylbenzene 
• 3748-13-8 1,3-bis(1-methylethenyl)-benzene 
• 67-56-1 methanol 
• 626-19-7 Isophthalaldehyde 
• 860517-17-5 2',3',2'',3''-tetrabromo-m-phenylene-di-propionate dimethyl ester 
• 4843-46-3 3,3′-(1,3-phenylene)dipropiolic acid 
• 23746-59-0 (E)-3-[3-((E)-2-methoxycarbonyl-vinyl)-phenyl]-acrylic acid methyl ester 

Downstream Products

• 132843-69-7 (2E,2'E)-1,1'-(1,3-phenylene)bis(3-(4-methoxyphenyl)prop-2-en-1-one) 
• 113786-94-0 1,3-bis<1-hydroxy-1-(pyridin-2-yl)ethyl>benzene 
• 87533-31-1 1’,3’-dimethyl-1,3-bis-aminoguanidine phenyl hydrazone dihydrochloride 
• 138336-93-3 1,3-bis-(4-methylthio-2,2'-bipyridin-6-yl)benzene 
• 87533-48-0 C₁₆H₂₂N₈*2BrH 
• 129005-67-0 1.4-Bis-(4-methyl-cinnamoyl)-benzol 
• 55147-57-4 1.4-Bis-(4-chlor-cinnamoyl)-benzol 
• 55147-58-5 1,1'-(1,3-phenylene)bis(3-phenyl-2-propen-1-one) 
• 129005-68-1 (Z)-3-(4-Isopropyl-phenyl)-1-{3-[(Z)-3-(4-isopropyl-phenyl)-acryloyl]-phenyl}-propenone 
• 132843-73-3 (2E,2'E)-1,1'-(1,3-phenylene)bis(3-(2,4-dimethoxyphenyl)prop-2-en-1-one) 
• 1294454-99-1 γ,γ'-dioxo-1,3-benzenedibutanenitrile 
• 1294455-12-1 γ,γ'-dioxo-1,3-benzenedibutanoic acid 
• 1294455-03-0 (3R,3'R,7aR,7a'R)-1,3-bis(5-oxo-3-phenyl-2,3,5,6,7,7a-hexahydropyrrolo[2,1-b]oxazol-7a-yl)benzene 
• 1294455-06-3 (5S,5'S)-1,3-bis{1-[(1R)-2-hydroxy-1-phenylethyl]-2-oxo-5-pyrrolidinyl}benzene 

Relevant articles and documents

Preparation method 1,3 - diacyl benzene

The preparation method of 1-3 - diacyl benzene comprises the following steps: reacting m-phthalic aldehyde with an alkyl magnesium halide to form an intermediate as shown II. The intermediate shown in Formula II is subjected to an oxidation reaction under the action of an oxidant to generate III, 1 diacyl benzene as shown 3 . In-flight R1 . R2 Alkyl groups from the alkyl magnesium halides, respectively. The method has the advantages of simple process, safety, environmental protection, high target product yield, high purity and the like, and can realize large-scale industrial production.

Photoinduced Acetylation of Anilines under Aqueous and Catalyst-Free Conditions

A green and efficient visible-light induced functionalization of anilines under mild conditions has been reported. Utilizing nontoxic, cost-effective, and water-soluble diacetyl as photosensitizer and acetylating reagent, and water as the solvent, a variety of anilines were converted into the corresponding aryl ketones, iodides, and bromides. With advantages of environmentally friendly conditions, simple operation, broad substrate scope, and functional group tolerance, this reaction represents a valuable method in organic synthesis.

Method for removing acyl group in diazo of aryl diazonium salt

The invention provides a method for removing an acyl group in diazo of an aryl diazonium salt. The method is characterized in that the aryl diazonium salt and its derivative and an ortho-dicarbonyl compound undergo an illumination reaction to obtain a corresponding arylacyl product. The method has the advantages of high yield of the product, no metal involvement, and simple process.