678144-71-3

Upstream product

• 156483-24-8 3-(4-bromobenzyl)-6-nitro-2-propyl-3,4-dihydroquinazolin-4-one 
• 163520-14-7 5-isobutyl-2 -(tert-butylaminosulfonyl)-3-thiopheneboronic acid 

Downstream Products

• 678144-97-3 N-benzyl-N-{3-[4-(2-tert-butylsulfamoyl-5-isobutyl-thiophen-3-yl)-benzyl]-4-oxo-2-propyl-3,4-dihydro-quinazolin-6-yl}-benzamide 
• 678144-98-4 thiophene-2-carboxylic acid benzyl-{3-[4-(2-tert-butylsulfamoyl-5-isobutyl-thiophen-3-yl)-benzyl]-4-oxo-2-propyl-3,4-dihydro-quinazolin-6-yl}-amide 
• 678144-96-2 pentanoic acid benzyl-{3-[4-(2-tert-butylsulfamoyl-5-isobutyl-thiophen-3-yl)-benzyl]-4-oxo-2-propyl-3,4-dihydro-quinazolin-6-yl}-amide 
• 678144-94-0 thiophene-2-carboxylic acid {3-[4-(2-tert-butylsulfamoyl-5-isobutyl-thiophen-3-yl)-benzyl]-4-oxo-2-propyl-3,4-dihydro-quinazolin-6-yl}-ethyl-amide 
• 678144-95-1 N-benzyl-N-{3-[4-(2-tert-butylsulfamoyl-5-isobutyl-thiophen-3-yl)-benzyl]-4-oxo-2-propyl-3,4-dihydro-quinazolin-6-yl}-acetamide 
• 678144-93-9 N-{3-[4-(2-tert-butylsulfamoyl-5-isobutyl-thiophen-3-yl)-benzyl]-4-oxo-2-propyl-3,4-dihydro-quinazolin-6-yl}-N-ethyl-benzamide 
• 678144-84-8 thiophene-2-carboxylic acid {3-[4-(2-tert-butylsulfamoyl-5-isobutyl-thiophen-3-yl)-benzyl]-4-oxo-2-propyl-3,4-dihydro-quinazolin-6-yl}-amide 
• 678144-81-5 N-{3-[4-(2-tert-butylsulfamoyl-5-isobutyl-thiophen-3-yl)-benzyl]-4-oxo-2-propyl-3,4-dihydro-quinazolin-6-yl}-benzamide 
• 678144-89-3 3-(4-{[6-(benzylamino)-4-oxo-2-propyl-3,4-dihydroquinazolin-3-yl]methyl}phenyl)-N-tert-butyl-5-isobutylthiophene-2-sulfonamide 

Relevant academic research and scientific papers

First Reported Nonpeptide AT1 Receptor Agonist (L-162,313) Acts as an AT2 Receptor Agonist in Vivo

In this investigation, it is demonstrated that the first nonpeptide AT 1 receptor agonist L-162,313 (1), disclosed in 1994, also acts as an agonist at the AT2 receptor. In anesthetized rats, administration of compound 1 intravenously