67815-57-0

Usage

Appearance

Colorless, crystalline solid

Solubility

Insoluble in water

Usage

Primarily used in organic synthesis as a building block for the preparation of various compounds

Chemical properties

Presence of iodine and fluorine in its structure gives it unique chemical properties

Applications

Useful in a variety of reactions in the pharmaceutical and chemical industries

Precursor

Used as a precursor for the synthesis of various biologically active molecules

Material development

Utilized in the development of new materials with specific properties

Safety

Should be handled with care due to its toxic and potentially harmful effects if not used properly

InChI:InChI=1/C6F4I2/c7-1-2(8)5(11)4(10)6(12)3(1)9

Upstream product

• 2367-82-0 1,2,3,5-tetrafluorobenzene 

Downstream Products

• 113705-13-8 1,3-bis((trimethylsilyl)ethynyl)tetrafluorobenzene 

Relevant academic research and scientific papers

In situ generation and trapping of aryllithium and arylpotassium species by halogen, sulfur, and carbon electrophiles

(Chemical Equation Presented) A general method has been developed for in situ trapping of arylmetal intermediates by halogen, sulfur, ketone, and aldehyde electrophiles affording the functionalization of the most acidic position in arene. Pentafluorobenzene, benzothiazole, and benzoxazole can be functionalized by using K3PO4 base. For less acidic arenes, tBuOLi base is required. Arenes with DMSO pKa values of 35 or less are reactive. 2009 American Chemical Society.

Diethynyl monomers and polymers thereof

The compound 1,3-diethynyl tetrafluorobenzene, and compounds having the structure STR1 represents a perfluorinated benzene ring and X represents oxygen or sulfur, as well as homopolymers and copolymers thereof.

Synthesis of High Carbon Materials from Acetylenic Precursors. Preparation of Aromatic Monomers Bearing Multiple Ethynyl Groups

The synthesis of polyethynyl aromatics as starting materials for the preparation of highly cross-linked organic solids containing high atom fractions of carbon is described.Treatment of bromo- and iodoaromatic compounds with (trimethylsilyl)acetylene (TMSA) in the presence of palladium(O) and copper(I) in amine solvents yields (trimethylsilyl)ethynyl-substituted aromatics.The TMS protecting groups can be removed by hydrolysis with mild base.Compounds prepared by using this technique include 1,3-diethynylbenzene, 2,5-diethynylthiophene, 1,3-diethynyltetrafluorobenzene, 1,4-diethynyltetrafluorobenzene, 2-ethynylthiazole, 2,4-diethynylthiazole, 2,7-diethynylnaphthalene, hexakis((trimethylsilyl)ethynyl)benzene, tetraethynylthiophene, 2,5-bis((trimethylsilyl)ethynyl)-3,4-bis(3-hydroxy-3-methyl-1-butynyl)thiophene, 2,5-diethynyl-3,4-bis(3-hydroxy-3-methyl-1-butynyl)thiophene, 2,5-bis(4-(2-thienyl)butadiynyl)-3,4-bis(3-hydroxy-3-methyl-1-butynyl)thiophene, and 2,5-bis-(4-(2-thienyl)butadiynyl)-3,4-diethynylthiophene.

Organothallium Compounds. XVIII The Effect of Antimony Pentafluoride and Fluorosulfuric Acid on the Thallation of Polyfluoroarenes

The polyfluoroarenes m-H2C6F4, m-O2NC6F4H, m- and p-BrC6F4H, (p-HC6F4)2, C6F5H, 1,3,5-F3C6H3 and m-FSO2C6F4H have been thallated by thallic trifluoroacetate in fluorosulfuric acid in the presence of antimony pentafluoride.Substantial dithallation of m-H2C6F4 and 1,3,5-F3C6H3 and slight trithallation of the latter have been achieved.The products were identified by conversion into the corresponding polyfluoroiodoarenes on reaction with aqueous sodium iodide.From the reaction with pentafluorobenzene, pentafluorophenylthallium(III) species have been characterized. 1,2,4,5-Tetrafluoro-3-methoxybenzene was thallated by thallic trifluoroacetate in 1,2-dichloroethane in the presence of boron trifluoride etherate, but C6F5H and p-MeC6F4H failed to react.