678159-96-1

Upstream product

• 678160-22-0 1-[(2S,3S,3aR,5R,6aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-1-((1S,3aS,7aS)-4,4,7a-trimethyl-octahydro-inden-1-yl)-ethanol 
• 876173-72-7 2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-carbaldehyde 
• 876173-68-1 2-[2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-ethanol 
• 876173-69-2 tert-butyl-[3-(2-iodo-ethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-2-ylmethoxy]-diphenyl-silane 
• 876173-47-6 dithiocarbonic acid O-[3-(tert-butyl-diphenyl-silanyloxy)-3a,7,7-trimethyl-octahydro-inden-1-yl] ester S-methyl ester 
• 876173-70-5 tert-butyl-[5-methoxy-3-(2-phenylselanyl-ethyl)-hexahydro-furo[2,3-b]furan-2-ylmethoxy]-diphenyl-silane 
• 876173-74-9 [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-(4,4,7a-trimethyl-3a,4,5,6,7,7a-hexahydro-3H-inden-1-yl)-methanone 
• 876173-73-8 [2-(tert-butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-yl]-(4,4,7a-trimethyl-3a,4,5,6,7,7a-hexahydro-3H-inden-1-yl)-methanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 678159-97-2 (-)-(3aS,7aS)-3-iodo-3a,7,7-trimethyl-3a,4,5,6,7,7a-hexahydro-1H-indene 
• 678160-18-4 (+)-(1S,3aS,7aS)-4,4,7a-trimethyloctahydro-1H-inden-1-ol 
• 678160-04-8 (+)-(3aS,7aS)-4,4,7a-trimethyloctahydro-1H-inden-1-one 
• 876173-48-7 (+)-(3aS,7aS)-4,4,7a-trimethyloctahydro-1H-inden-1-one hydrazone 
• 678159-98-3 (2S,3S,3aR,5R,6aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5-methoxy-hexahydro-furo[2,3-b]furan-3-carbaldehyde 

Relevant academic research and scientific papers

Norrisolide: Total synthesis and related studies

A stereoselective synthesis of (+)-norrisolide is presented. This natural product belongs to a family of marine spongiane diterpenes the structure of which is characterized by a fused γ-lactone-γ-lactol ring system attached to a bicyclic hydrophobic core.

Stereoselective Total Synthesis of (+)-Norrisolide

In a convergent approach to the marine natural product (+)-norrisolide (1) the two bicyclic ring systems are coupled through the C9-C10 bond to assemble the carbon framework in a late stage of the synthesis. Other highlights of the synthetic strategy incl