67817-85-0Relevant academic research and scientific papers
Oral hypoglycaemic agents
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, (2008/06/13)
Compounds of formula (I) which are optionally substituted 2-(ω,ω-diarylalkyl)-4,5-dihydro-1H-imidazoles and 2-(ω,ω-diarylalkyl)-1,4,5,6-tetrahydropyrimidines and salts thereof with inorganic and organic acids have interesting pharmacological properties. T
Treatment of diabetes with 2-substituted-1,3-diazacyclic compounds
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, (2008/06/13)
2-SUBSTITUTED-1,3-DIAZACYCLIC COMPOUNDS OF THE FORMULA: STR1 wherein R1 represents a hydrogen atom, a halogen atom, a lower alkyl group or a lower alkoxy group; R2 represents a hydrogen atom, a lower alkoxycarbonyl group, an aliphatic acyl group or an aromatic acyl group, the aromatic ring of which may have one or more substituents selected from a halogen atom, a lower alkyl group, a lower alkoxy group, an acyl group and an acyloxy group; R3 represents a hydrogen atom, a lower alkyl group, a lower hydroxyalkyl group or an aralkyl group; R4 represents a hydrogen atom, a lower alkyl group or an aryl group; R6 represents a cyclohexyl group, a pyridyl group or a phenyl group which may have a substituent selected from a halogen atom, a lower alkyl group and a lower alkoxy group; A represents -N=, an -N(lower alkyl)- group or a methylene group; n represents an integer of from 2 to 4, and a dotted line indicates that a double bond is optional; salts of such derivatives; and the method for preparing such compounds and their salts; the compounds and their salts having a distinct anti-diabetic activity in humans and animals.
