678172-34-4

Upstream product

• 76-83-5 trityl chloride 
• 527758-24-3 Methanesulfonic acid (S)-4-methanesulfonyloxy-2-trityloxy-butyl ester 
• 527758-12-9 dimethyl (S)-malate trityl ether 
• 485321-76-4 (S)-2-Trityloxy-butane-1,4-diol 
• 69555-14-2 ethyl N-diphenylmethylene glycine 
• 527758-14-1 1,4-diiodo-2(S)-trityl-oxybutane 

Downstream Products

• 527758-30-1 3-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-1-tert-butoxycarbonylamino-cyclopentanecarboxylic acid ethyl ester 
• 527758-26-5 3-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-1-tert-butoxycarbonylamino-cyclopentanecarboxylic acid ethyl ester 
• 527758-29-8 3-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-1-tert-butoxycarbonylamino-cyclopentanecarboxylic acid ethyl ester 
• 527758-25-4 3-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-1-tert-butoxycarbonylamino-cyclopentanecarboxylic acid ethyl ester 
• 527758-17-4 (1R,3S)-3-(4-Bromo-benzenesulfonyloxy)-1-tert-butoxycarbonylamino-cyclopentanecarboxylic acid ethyl ester 
• 527758-16-3 (1S,3S)-3-(4-Bromo-benzenesulfonyloxy)-1-tert-butoxycarbonylamino-cyclopentanecarboxylic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis of the four diastereoisomers of 3-thymine-1-(tbutoxycarbonyl)aminocyclopentane-1-carboxylic acid

Synthetic routes to all four diastereoisomers of 3-thymine-1-(tbutoxycarbonyl)aminocyclopentane-1-carboxylic acid have been developed starting from the commercially available (S)-dimethyl malate. The key step in the synthesis involves dialkylat

α-cycloPNA: 1-Aminocylopentane-1-carboxylic acid-derived peptide nucleic acid

All four diastereoisomers of 3-thymine-1-( tbutoxycarbonyl)aminocyclopentane-1-carboxylic acid have been synthesised from (S)-dimethyl malate and thymine monomer 12 has been incorporated into an α-cycloPNA oligomer.