67838-10-2Relevant academic research and scientific papers
Geminal prostaglandin analogs
-
, (2008/06/13)
Geminal prostaglandins (P.G.'s) are synthesized which are represented by the general formula: STR1 where A is a 4 or 5 carbon atom ring-completing group (CH2)1+m --X--(CH2)z where m = 0, 1 or 2, Z = 0 or 1, 02 --CH2 --, --CH2 --CHOH--, STR2 and, when m = 0 and z = 1, is also --CH=CH-- or STR3 Y is divalent straight chain alkylene of 4 to 8 carbon atoms or r is alkyl of 4 to 7 carbon atoms; Q is --CO2 H or --CH2 OH provided that it is not --CH2 OH when X = STR4 or Y--Q taken together may be heptyl or allyl.
