67858-48-4

Usage

Derivative of pyrrole

The compound is derived from pyrrole, which is a five-membered heterocyclic aromatic compound containing one nitrogen atom.

Two carboxylic acid groups

The compound contains two carboxylic acid groups (-COOH), which contribute to its acidic properties and make it capable of forming salts or esters.

Methyl ester group

The compound also contains a methyl ester group (-COOCH3), which is formed by the esterification of one of the carboxylic acid groups with methanol (CH3OH).

Potential applications in organic synthesis

1H-Pyrrole-2,4-dicarboxylic acid 2-Methyl ester can be used as a building block for the synthesis of various organic molecules, making it a valuable intermediate in organic chemistry.

Potential applications in medicinal chemistry

The compound can be used in the development of pharmaceuticals, as its structure and reactivity can be exploited to create new drug compounds.

Valuable tool for research

Due to its unique properties and reactivity, 1H-Pyrrole-2,4-dicarboxylic acid 2-Methyl ester is a valuable tool for researchers in the development of new materials and drug compounds.

Upstream product

• 40611-79-8 methyl 4-formyl-1H-pyrrole-2-carboxylate 

Downstream Products

• 929017-80-1 1-oxo-2-[2-(4-piperidin-1-ylmethyl-phenyl)-ethyl]-1,2,3,4-tetrahydro-pyrrolo[1,2-a]pyrazine-7-carboxylic acid 
• 2818-07-7 pyrrole-2,4-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry

Libraries of DNA-Encoded small molecules created using combinatorial chemistry and synthetic oligonucleotides are being applied to drug discovery projects across the pharmaceutical industry. The majority of reported projects describe the discovery of reve

Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists

The synthesis and biological testing of novel classes of potent melanin-concentrating hormone (MCH-R1) antagonists based on pyrazolopiperazinone and pyrrolopiperazinone scaffolds are described.

Synthesis and characterization of Boc-protected 4-amino- and 5-amino-pyrrole-2-carboxylic acid methyl esters

Syntheses of Boc-protected 4-amino- and 5-amino-pyrrole-2-carboxylic acid methyl esters have been achieved and the structures of these compounds have been fully characterized by detailed NMR studies.

Pyrrole-derivatives as factor Xa inhibitors

The present invention relates to compounds of the formulae I and Ia, wherein R0 ; R1 ; R2 ; R3 ; R4; R22, Q; V, G and M have the meanings indicated in the claims. The compounds of the formulae I and Ia are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formulae I and Ia, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.