6786-41-0 Usage
Uses
Used in Pharmaceutical Industry:
Spiro[indoline-3,3'-pyrrolidin]-2-one is utilized as a core structure in the synthesis of biologically active molecules for various therapeutic applications. Its pharmacological activities, including anti-inflammatory, anti-tumor, and analgesic effects, make it a valuable compound in the development of new drugs.
Used in Medicinal Chemistry Research:
As an important intermediate in medicinal chemistry, spiro[indoline-3,3'-pyrrolidin]-2-one is used for the synthesis of a wide range of biologically active molecules. Its unique spirocyclic structure allows for the creation of diverse compounds with potential therapeutic benefits.
Used in Asymmetric Synthesis:
Spiro[indoline-3,3'-pyrrolidin]-2-one serves as a chiral building block in the development of enantioselective catalysts and ligands for asymmetric synthesis. Its ability to create enantiomerically pure compounds is crucial in the synthesis of pharmaceuticals and other chiral molecules, where the stereochemistry can significantly impact the biological activity and safety of the final product.
Used in Chemical Synthesis:
Due to its unique structure and potential applications, spiro[indoline-3,3'-pyrrolidin]-2-one is a valuable target for chemical synthesis. Researchers are interested in exploring its synthetic routes and modifications to enhance its properties and expand its applications in various fields, including pharmaceuticals, materials science, and catalysis.
Check Digit Verification of cas no
The CAS Registry Mumber 6786-41-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,8 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6786-41:
(6*6)+(5*7)+(4*8)+(3*6)+(2*4)+(1*1)=130
130 % 10 = 0
So 6786-41-0 is a valid CAS Registry Number.
6786-41-0Relevant academic research and scientific papers
Synthesis of (±)-coerulescine and a formal synthesis of (±)-horsfiline
Chang, Meng-Yang,Pai, Chun-Li,Kung, Yung-Hua
, p. 8463 - 8465 (2007/10/03)
A straightforward synthesis of (±)-coerulescine and (±)-horsfiline has been established from 3-formyl-3-phenylpyrrolidine employing 4-hydroxypiperidine as the starting material. There are two remarkable steps for the synthesis of (±)-coerulescine and (±)-horsfiline. One is the rapid access to produce 3-formyl-3-phenylpyrrolidine by Lewis acid-catalyzed rearrangement of 3,4-dihydroxy-4-phenylpiperidine. The other key step is an intramolecular electrophilic cyclization from 3-benzylcarbamoyl-3- phenylpyrrolidine to the 3,3-spirocyclic 2-oxindole ring skeleton.
Preparation and a novel rearrangement reaction of 1,2,3,4-tetrahydro-9- hydroxy-β-carboline, and their applications for the total synthesis of (±)- coerulescine
Somei,Noguchi,Yamagami,Kawada,Yamada,Yamada
, p. 7 - 10 (2007/10/03)
Novel 9-hydroxy-β-carboline derivatives were produced for the first time. A novel rearrangement reaction of 1,2,3,4-tetrahydro-9-hydroxy-β- carbolines was discovered to give 3,3-disubstituted oxindoles, which was successfully applied to the total synthesis of (±)-coerulescine.
