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U-2-<1-(4-methoxyphenyl)-2-nitroethyl>-cyclohexanone is a complex organic compound with the molecular formula C15H19NO4. It is a derivative of cyclohexanone, featuring a nitroethyl group attached to the cyclohexane ring, with a 4-methoxyphenyl substituent on the nitrogen atom. u-2-<1-(4-methoxyphenyl)-2-nitroethyl>-cyclohexanone is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals due to its unique structural properties. The presence of the nitro group and the methoxyphenyl group can influence its reactivity and interactions with other molecules, making it a compound of interest in chemical research and development.

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  • 67861-09-0 Structure
  • Basic information

    1. Product Name: u-2-<1-(4-methoxyphenyl)-2-nitroethyl>-cyclohexanone
    2. Synonyms:
    3. CAS NO:67861-09-0
    4. Molecular Formula:
    5. Molecular Weight: 277.32
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 67861-09-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: u-2-<1-(4-methoxyphenyl)-2-nitroethyl>-cyclohexanone(CAS DataBase Reference)
    10. NIST Chemistry Reference: u-2-<1-(4-methoxyphenyl)-2-nitroethyl>-cyclohexanone(67861-09-0)
    11. EPA Substance Registry System: u-2-<1-(4-methoxyphenyl)-2-nitroethyl>-cyclohexanone(67861-09-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 67861-09-0(Hazardous Substances Data)

67861-09-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 67861-09-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,8,6 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 67861-09:
(7*6)+(6*7)+(5*8)+(4*6)+(3*1)+(2*0)+(1*9)=160
160 % 10 = 0
So 67861-09-0 is a valid CAS Registry Number.

67861-09-0Downstream Products

67861-09-0Relevant articles and documents

A novel mesoporous silica-grafted organocatalyst for the Michael addition reaction, synthesized via the click method

Jain, Suman L.,Modak, Arindam,Bhaumik, Asim

, p. 586 - 590 (2011)

An efficient and recyclable mesoporous silica-grafted bifunctional acid-base organocatalyst for the Michael addition of ketones to β-nitrostyrenes has been synthesized by click chemistry, affording the products with excellent diastereoselectivity. A remar

N-Pyrrolidine-2-ylmethyl)-2-hydroxy-3-aminopinanes as novel organocatalysts for asymmetric conjugate additions of ketones to α-nitroalkenes

Siyutkin, Dmitry E.,Kucherenko, Alexander S.,Frolova, Larisa L.,Kuchin, Alexander V.,Zlotin, Sergei G.

, p. 776 - 779 (2013/07/25)

Novel stereoisomeric natural pinane-derived bifunctional catalysts 3a-d bearing a pyrrolidine unit have been synthesized and examined in the asymmetric conjugate additions of carbonyl compounds to α-nitroalkenes. Six-membered cyclic ketones react with β-n

Acidic proteinase from Aspergillus usamii catalyzed Michael addition of ketones to nitroolefins

Xu, Ke-Ling,Guan, Zhi,He, Yan-Hong

body text, p. 108 - 112 (2012/01/13)

A new promiscuous activity of AUAP (acidic proteinase from Aspergillus usamii) was investigated in Michael addition of cyclic and acyclic ketones to aromatic and heteroaromatic nitroolefins in organic media in the presence of water. The yields were obtain

C3-symmetric proline-functionalized organocatalysts: Enantioselective michael addition reactions

Moorthy, Jarugu Narasimha,Saha, Satyajit

supporting information; experimental part, p. 6359 - 6365 (2011/03/17)

C3-Symmetric, tripodal catalyst 4 based on 1,3,5- triethylbenzene, which incorporates the features of a molecular receptor, is shown to catalyze Michael addition reactions ofcarbonyl compounds to β-nitrostyrenes in a high stereoselectivity (up to 99:1a dr and up to 98%ee). Copyright

Cyclic nitronates from the diastereoselective addition of 1-trimethylsilyloxycyclohexene to nitroolefins. Starting materials for stereoselective Henry reactions and 1,3-dipolar cycloadditions

Brook, Michael A.,Seebach, Dieter

, p. 836 - 850 (2007/10/02)

Induced by a stoichiometric excess of dichloro(diisopropoxy)-titanium, 1-trimethylsilyloxycyclohexene and (E)-nitroolefins (R-CH=CHNO2, R = C6H5, p-C6H4CH3, p-C6H4OCH3, p-C6H4CN, CH3) combine in CH2Cl2 solution at -90 deg C preferentially with relative topicity ul, opposite to the corresponding reaction of enolates or enamines.The primary products are the epimeric bicyclic nitronates 4-6, which can be separated, and which are converted by KF in MeOH to the alkyl or aryl (nitroethyl)-substituted cyclohexanones 1 and 2 (Table 1).Instead of being solvolysed, the cyclic nitronates 4-6 can be used for nitroaldol additions to give the trisubstituted hexahydrobenzopyranols 15-19.Alternatively, 4-6 can be used in 1,3-dipolar cycloadditions with acrylates to furnish the tricyclic compounds 22-31.In either case, products with four asymmetric carbon atoms (not including acetal centres) are produced diastereoselectively.The addition described here is yet another example of an ul combination of trigonal centres induced by Lewis acids, overriding the influence of the configuration of the donor component.

Reversed Stereochemical Course of the Michael Addition of Cyclohexanone to β-nitrostyrenes by Using 1-(Trimethylsiloxy)cyclohexene/Dichloro(diisopropoxy)titanium

Seebach, Dieter,Brook, Michael A.

, p. 319 - 324 (2007/10/02)

Induced by a stoichiometric excess of dichloro(diisopropoxy)titanium, 1-(trimethylsiloxy)cyclohexene and p-substituted β-nitrostyrenes (Y=H, CH3, CH3O, CN) combine in CH2Cl2 solution at -90 deg preferentially with relative topicity ul - opposite to the co

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